Literature DB >> 33493493

Many Young Children with Autism Who Use Psychotropic Medication Do Not Receive Behavior Therapy: A Multisite Case-Control Study.

Lisa D Wiggins1, Cy Nadler2, Steven Rosenberg3, Eric Moody4, Nuri Reyes3, Ann Reynolds3, Aimee Alexander5, Julie Daniels6, Kathleen Thomas7, Ellen Giarelli8, Susan E Levy9.   

Abstract

OBJECTIVES: To explore how many pre-school aged children with autism spectrum disorder (ASD) used psychotropic medication, child and geographic factors associated with psychotropic medication use, and how many children who used psychotropic medication did or did not ever receive behavior therapy. STUDY
DESIGN: Children 2-5 years of age were enrolled from 2012 to 2016 in a multisite case-control study designed to investigate the development and risk factors of ASD. Children with a positive ASD screen or ASD diagnosis upon enrollment were asked to complete a comprehensive evaluation to determine ASD status and developmental level. Caregivers completed a Services and Treatments Questionnaire and multiple self-administered questionnaires to determine child use of psychotropic medication, ever receipt of behavior therapy, and presence of co-occurring symptoms.
RESULTS: There were 763 children who were classified as ASD and had data collected on the Services and Treatments Questionnaire. Of those, 62 (8.1%) used psychotropic medication to treat behavioral symptoms and 28 (3.7%) were ≤3 years of age when medication was first started. Attention problems (aOR, 7.65; 95% CI, 3.41-16.1; P < .001) and study site (aOR, 2.62; 95% CI, 1.04-6.56; P = .04) were significantly associated with psychotropic medication use after controlling for maternal race/ethnicity. More than one-half (59.7%) of those who used psychotropic medication did not ever receive behavior therapy.
CONCLUSIONS: Many preschool-aged children with ASD who use psychotropic medication do not receive behavior therapy. Pediatricians are an important resource for children and families and can help facilitate behavioral treatment for children with ASD and other disorders.
Copyright © 2021 Elsevier Inc. All rights reserved.

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Year:  2021        PMID: 33493493      PMCID: PMC8174527          DOI: 10.1016/j.jpeds.2021.01.043

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   6.314


  54 in total

1.  Treatment incidence and patterns in children and adolescents with autism spectrum disorders.

Authors:  Andrea Witwer; Luc Lecavalier
Journal:  J Child Adolesc Psychopharmacol       Date:  2005-08       Impact factor: 2.576

2.  Psychotropic medication use among children with autism spectrum disorders enrolled in a national registry, 2007-2008.

Authors:  Rebecca E Rosenberg; David S Mandell; Janet E Farmer; J Kiely Law; Alison R Marvin; Paul A Law
Journal:  J Autism Dev Disord       Date:  2010-03

3.  Using standardized diagnostic instruments to classify children with autism in the study to explore early development.

Authors:  Lisa D Wiggins; Ann Reynolds; Catherine E Rice; Eric J Moody; Pilar Bernal; Lisa Blaskey; Steven A Rosenberg; Li-Ching Lee; Susan E Levy
Journal:  J Autism Dev Disord       Date:  2015-05

Review 4.  Evidence Base Update for Autism Spectrum Disorder.

Authors:  Tristram Smith; Suzannah Iadarola
Journal:  J Clin Child Adolesc Psychol       Date:  2015

Review 5.  Efficacy of early interventions for infants and young children with, and at risk for, autism spectrum disorders.

Authors:  Rebecca J Landa
Journal:  Int Rev Psychiatry       Date:  2018-03-14

6.  The Autism Diagnostic Observation Schedule: revised algorithms for improved diagnostic validity.

Authors:  Katherine Gotham; Susan Risi; Andrew Pickles; Catherine Lord
Journal:  J Autism Dev Disord       Date:  2006-12-16

Review 7.  Use of psychotropic drugs in patients with autism spectrum disorders: a systematic review.

Authors:  K Jobski; J Höfer; F Hoffmann; C Bachmann
Journal:  Acta Psychiatr Scand       Date:  2016-09-13       Impact factor: 6.392

8.  Medicaid expenditures on psychotropic medications for maltreated children: a study of 36 States.

Authors:  Ramesh Raghavan; Derek S Brown; Benjamin T Allaire; Lauren D Garfield; Raven E Ross
Journal:  Psychiatr Serv       Date:  2014-11-17       Impact factor: 3.084

Review 9.  Treatment of inattention, overactivity, and impulsiveness in autism spectrum disorders.

Authors:  Michael G Aman; Cristan A Farmer; Jill Hollway; L Eugene Arnold
Journal:  Child Adolesc Psychiatr Clin N Am       Date:  2008-10

10.  Society for Developmental and Behavioral Pediatrics Clinical Practice Guideline for the Assessment and Treatment of Children and Adolescents with Complex Attention-Deficit/Hyperactivity Disorder.

Authors:  William J Barbaresi; Lisa Campbell; Elizabeth A Diekroger; Tanya E Froehlich; Yi Hui Liu; Eva O'Malley; William E Pelham; Thomas J Power; Samuel H Zinner; Eugenia Chan
Journal:  J Dev Behav Pediatr       Date:  2020 Feb/Mar       Impact factor: 2.225

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