Literature DB >> 3349339

Treatment policy for the management of carcinoma of the oesophagus.

L Desa1, A S Raghunath, S L Chawla, A L Peel, A W Dellipiani.   

Abstract

The management of 120 consecutive patients with carcinoma of the oesophagus, treated in a district general hospital over a 10-year period is reviewed. The treatment options were by endoscopic methods, radiotherapy, surgery or a combination of these. Adenocarcinoma was the most frequent histological type (51 per cent) and 41 per cent of patients had squamous carcinoma. In addition to survival the quality of swallowing and the incidence of late complications following the treatment options was assessed. Primary surgery was carried out in 21 cases (operability rate 17.5 per cent) and 81 per cent of these cases were resectable. The overall operative mortality rate was 14.3 per cent (6 per cent in resected cases) and the 5-year survival rate was 9.5 per cent. After primary radiotherapy only 5 per cent of patients survived 2 years. The majority of patients were treated by endoscopic intubation with an overall mortality of 16.6 per cent and a mean survival of 5.5 months. Patients treated surgically experienced the best symptomatic relief and had the lowest incidence of late complications, when compared with those treated differently. However the overall results of surgery were poor and there remains the need to compare the results of surgery and radiotherapy in similar groups of patients.

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Mesh:

Year:  1988        PMID: 3349339     DOI: 10.1002/bjs.1800750329

Source DB:  PubMed          Journal:  Br J Surg        ISSN: 0007-1323            Impact factor:   6.939


  8 in total

1.  Palliative bipolar electrocoagulation treatment of malignant gastroesophageal strictures.

Authors:  M Conio; L Bonelli; H Martines; F Munizzi; H Aste
Journal:  Surg Endosc       Date:  1990       Impact factor: 4.584

2.  Laser and brachytherapy in the palliation of adenocarcinoma of the oesophagus and cardia.

Authors:  G M Spencer; S M Thorpe; I R Sargeant; G M Blackman; J Solano; J S Tobias; S G Bown
Journal:  Gut       Date:  1996-11       Impact factor: 23.059

Review 3.  Surgical management of carcinoma of the esophagus.

Authors:  J C Harvey; E J Beattie
Journal:  Bull N Y Acad Med       Date:  1993 Jan-Feb

Review 4.  Comparison of different treatments for unresectable esophageal cancer.

Authors:  C E Reed
Journal:  World J Surg       Date:  1995 Nov-Dec       Impact factor: 3.352

5.  Cancer of the oesophagus.

Authors:  S E Oliver; R F Logan
Journal:  Gut       Date:  1995-01       Impact factor: 23.059

6.  Does esophagectomy cure a resectable esophageal cancer?

Authors:  I el Nakadi; J J Houben; F Gay; J Closset; M Gelin; J P Lambilliotte
Journal:  World J Surg       Date:  1993 Nov-Dec       Impact factor: 3.352

7.  Selection for oesophagectomy and postoperative outcome in a defined population.

Authors:  M C Gulliford; J R Barton; H M Bourne
Journal:  Qual Health Care       Date:  1993-03

8.  What does radiotherapy add to survival over endoscopic intubation alone in inoperable squamous cell oesophageal cancer?

Authors:  S E Oliver; C S Robertson; R F Logan; M Sokal; J C Pearson; M Atkinson
Journal:  Gut       Date:  1990-07       Impact factor: 23.059

  8 in total

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