François Freddy Ateba1,2, Seydou Doumbia1, Feiko O Ter Kuile3,4, Dianne J Terlouw3,5, Genevieve Lefebvre2, Simon Kariuki4, Dylan S Small6. 1. Malaria Research and Training Center & Department of Public Health Education and Research of the Faculty of Medicine and Odonto-Stomatology, University of Sciences, Techniques and Technologies of Bamako, BP 1805 Point G Bamako, Mali. 2. Department of Mathematics, University of Quebec at Montreal (UQAM), Montréal, QC H2X 3Y7, Canada. 3. Liverpool School of Tropical Medicine, Department of Clinical Sciences, Pembroke Place, Liverpool L3 5QA, UK. 4. Centre for Global Health Research, Kenya Medical Research Institute (KEMRI), P.O. Box 1578, 40100 Kisumu, Kenya. 5. Malawi-Liverpool Wellcome Trust Clinical Research Programme (MLW), P.O. Box 30096 Blantyre, Malawi. 6. Department of Statistics, Wharton School, University of Pennsylvania, 464 Jon M. Huntsman Hall 3730 Walnut Street Philadelphia, PA 19104 Philadelphia, PA, USA.
Abstract
BACKGROUND: Previous studies have found mixed evidence for an effect of malaria on stunting, but have suffered from concerns about confounding and/or power. Currently, an effect of malaria on stunting is not included in the Lives Saved Tool (LiST) model. METHODS: We used instrumental variables regression with the sickle cell trait and random assignment to bednets as instruments in the analysis of data on children aged 0-2 y from a bednet trial in western Kenya. RESULTS: We estimated that one additional clinical malaria episode per year increases the odds of a child being stunted by 6% (OR estimate: 1.06, 95% CI 1.01 to 1.11). CONCLUSIONS: Our finding that malaria affects stunting suggests that an effect of malaria on stunting in young children should be considered in the LiST model.
BACKGROUND: Previous studies have found mixed evidence for an effect of malaria on stunting, but have suffered from concerns about confounding and/or power. Currently, an effect of malaria on stunting is not included in the Lives Saved Tool (LiST) model. METHODS: We used instrumental variables regression with the sickle cell trait and random assignment to bednets as instruments in the analysis of data on children aged 0-2 y from a bednet trial in western Kenya. RESULTS: We estimated that one additional clinical malaria episode per year increases the odds of a child being stunted by 6% (OR estimate: 1.06, 95% CI 1.01 to 1.11). CONCLUSIONS: Our finding that malaria affects stunting suggests that an effect of malaria on stunting in young children should be considered in the LiST model.
Authors: Feiko O ter Kuile; Dianne J Terlouw; Simon K Kariuki; Penelope A Phillips-Howard; Lisa B Mirel; William A Hawley; Jennifer F Friedman; Ya Ping Shi; Margarette S Kolczak; Altaf A Lal; John M Vulule; Bernard L Nahlen Journal: Am J Trop Med Hyg Date: 2003-04 Impact factor: 2.345
Authors: Jane A Alaii; William A Hawley; Margarette S Kolczak; Feiko O ter Kuile; John E Gimnig; John M Vulule; Amos Odhacha; Aggrey J Oloo; Bernard L Nahlen; Penelope A Phillips-Howard Journal: Am J Trop Med Hyg Date: 2003-04 Impact factor: 2.345
Authors: Penelope A Phillips-Howard; Bernard L Nahlen; Jane A Alaii; Feiko O ter Kuile; John E Gimnig; Dianne J Terlouw; S Patrick Kachur; Allen W Hightower; Altaf A Lal; Erik Schoute; Aggrey J Oloo; William A Hawley Journal: Am J Trop Med Hyg Date: 2003-04 Impact factor: 2.345