Literature DB >> 33492049

Reimbursement Matters: Overcoming Barriers to Clinical Trial Accrual.

Simon J Craddock Lee1,2, Caitlin C Murphy1,2, David E Gerber1,2,3, Ann M Geiger4, Ethan Halm1,2,3, Rasmi G Nair1, John V Cox3, Jasmin A Tiro1,2, Celette S Skinner1,2.   

Abstract

BACKGROUND: Accrual to cancer clinical trials is suboptimal. Few data exist regarding whether financial reimbursement might increase accruals.
OBJECTIVE: The objective of this study was to assess perceptions about reimbursement to overcome barriers to trial accrual. RESEARCH
DESIGN: This was a cross-sectional survey.
SUBJECTS: Oncologists identified from the American Medical Association Physician Masterfile. MEASURES: We report descriptive statistics, associations of physician characteristics with perceptions of reimbursement, domains, and subthemes of free-text comments.
RESULTS: Respondents (n=1030) were mostly medical oncologists (59.4%), ages 35-54 (67%), and male (75%). Overall, 30% reported discussing trials with >25% of patients. Barriers perceived were administrative/regulatory, physician/staff time, and eligibility criteria. National Cancer Institute cooperative group participants and practice owners were more likely to endorse higher reimbursement. Respondents indicated targeted reimbursement would help improve infrastructure, but also noted potential ethical problems with reimbursement for discussion (40.7%) and accrual (85.9%). Free-text comments addressed reimbursement sources, recipients, and concerns about the real and apparent conflict of interest.
CONCLUSIONS: Though concerns about a potential conflict of interest remain paramount and must be addressed in any new system of reimbursement, oncologists believe reimbursement to enhance infrastructure could help overcome barriers to trial accrual.
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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Year:  2021        PMID: 33492049      PMCID: PMC8026490          DOI: 10.1097/MLR.0000000000001509

Source DB:  PubMed          Journal:  Med Care        ISSN: 0025-7079            Impact factor:   3.178


  22 in total

1.  Challenges to National Cancer Institute-Supported Cooperative Group Clinical Trial Participation: An ASCO Survey of Cooperative Group Sites.

Authors:  Allison R Baer; Chelsey A Kelly; Suanna S Bruinooge; Carolyn D Runowicz; Douglas W Blayney
Journal:  J Oncol Pract       Date:  2010-04-15       Impact factor: 3.840

2.  Cancer therapy costs influence treatment: a national survey of oncologists.

Authors:  Peter J Neumann; Jennifer A Palmer; Eric Nadler; Chihui Fang; Peter Ubel
Journal:  Health Aff (Millwood)       Date:  2010 Jan-Feb       Impact factor: 6.301

3.  Accrual to clinical trials: let's look at the physicians.

Authors:  Lori M Minasian; Ann M O'Mara
Journal:  J Natl Cancer Inst       Date:  2011-02-11       Impact factor: 13.506

4.  Conceptual Model for Accrual to Cancer Clinical Trials.

Authors:  Simon J Craddock Lee; Caitlin C Murphy; Ann M Geiger; David E Gerber; John V Cox; Rasmi Nair; Celette Sugg Skinner
Journal:  J Clin Oncol       Date:  2019-06-05       Impact factor: 44.544

Review 5.  Five Policy Levers To Meet The Value Challenge In Cancer Care.

Authors:  Ryan Callahan; Ara Darzi
Journal:  Health Aff (Millwood)       Date:  2015-09       Impact factor: 6.301

6.  Funding oncology clinical trials: are cooperative group trials sustainable?

Authors:  Hsien-Yeang Seow; Patrick Whelan; Mark N Levine; Kathryn Cowan; Barbara Lysakowski; Brenda Kowaleski; Anne Snider; Rebecca Y Xu; Andrew Arnold
Journal:  J Clin Oncol       Date:  2012-03-26       Impact factor: 44.544

7.  Invisible barriers to clinical trials: the impact of structural, infrastructural, and procedural barriers to opening oncology clinical trials.

Authors:  David M Dilts; Alan B Sandler
Journal:  J Clin Oncol       Date:  2006-10-01       Impact factor: 44.544

8.  The State of Oncology Practice in America, 2018: Results of the ASCO Practice Census Survey.

Authors:  M Kelsey Kirkwood; Amy Hanley; Suanna S Bruinooge; Elizabeth Garrett-Mayer; Laura A Levit; Caroline Schenkel; Jerome E Seid; Blase N Polite; Richard L Schilsky
Journal:  J Oncol Pract       Date:  2018-06-15       Impact factor: 3.840

9.  Trends In Orphan New Molecular Entities, 1983-2014: Half Were First In Class, And Rare Cancers Were The Most Frequent Target.

Authors:  Kathleen L Miller; Michael Lanthier
Journal:  Health Aff (Millwood)       Date:  2016-03       Impact factor: 6.301

10.  Screening for psychosocial distress: a national survey of oncologists.

Authors:  William F Pirl; Anna Muriel; Vivian Hwang; Alice Kornblith; Joseph Greer; Karen Donelan; Donna B Greenberg; Jennifer Temel; Lidia Schapira
Journal:  J Support Oncol       Date:  2007 Nov-Dec
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