Literature DB >> 33491561

Cooperative activation of divergent pathways by LPAR1 and LPAR2 receptors in fibrotic signaling.

Marpadga A Reddy1, Rama Natarajan1.   

Abstract

Entities:  

Keywords:  acute kidney injury; chronic kidney disease; fibrosis; lysophosphatidic acid; tubulointerstitial fibrosis

Mesh：

Substances：

Year:  2021        PMID： 33491561      PMCID： PMC7988805          DOI： 10.1152/ajprenal.00685.2020

Source DB:  PubMed          Journal:  Am J Physiol Renal Physiol        ISSN： 1522-1466


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  9 in total

Review 1.  Epigenetics and epigenomics in diabetic kidney disease and metabolic memory.

Authors:  Mitsuo Kato; Rama Natarajan
Journal:  Nat Rev Nephrol       Date:  2019-06       Impact factor: 28.314

2.  Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury.

Authors:  Li Yang; Tatiana Y Besschetnova; Craig R Brooks; Jagesh V Shah; Joseph V Bonventre
Journal:  Nat Med       Date:  2010-05-02       Impact factor: 53.440

Review 3.  Acute kidney injury and chronic kidney disease as interconnected syndromes.

Authors:  Lakhmir S Chawla; Paul W Eggers; Robert A Star; Paul L Kimmel
Journal:  N Engl J Med       Date:  2014-07-03       Impact factor: 91.245

Review 4.  Role of lysophosphatidic acid and its receptors in the kidney.

Authors:  Frank Park; Duane D Miller
Journal:  Physiol Genomics       Date:  2017-09-22       Impact factor: 3.107

5.  Blocking lysophosphatidic acid receptor 1 signaling inhibits diabetic nephropathy in db/db mice.

Authors:  Hui Ying Li; Yoon Sin Oh; Ji-Woong Choi; Ji Yong Jung; Hee-Sook Jun
Journal:  Kidney Int       Date:  2017-01-19       Impact factor: 10.612

6.  Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β.

Authors:  Hui Geng; Rongpei Lan; Prajjal K Singha; Annette Gilchrist; Paul H Weinreb; Shelia M Violette; Joel M Weinberg; Pothana Saikumar; Manjeri A Venkatachalam
Journal:  Am J Pathol       Date:  2012-08-10       Impact factor: 4.307

7.  LPA1 receptor activation promotes renal interstitial fibrosis.

Authors:  Jean-Philippe Pradère; Julie Klein; Sandra Grès; Charlotte Guigné; Eric Neau; Philippe Valet; Denis Calise; Jerold Chun; Jean-Loup Bascands; Jean-Sébastien Saulnier-Blache; Joost P Schanstra
Journal:  J Am Soc Nephrol       Date:  2007-11-14       Impact factor: 10.121

Review 8.  AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms.

Authors:  Liyu He; Qingqing Wei; Jing Liu; Mixuan Yi; Yu Liu; Hong Liu; Lin Sun; Youming Peng; Fuyou Liu; Manjeri A Venkatachalam; Zheng Dong
Journal:  Kidney Int       Date:  2017-09-08       Impact factor: 10.612

9.  Proximal tubule LPA1 and LPA2 receptors use divergent signaling pathways to additively increase profibrotic cytokine secretion.

Authors:  Hui Geng; Rongpei Lan; Yaguang Liu; Wei Chen; Meng Wu; Pothana Saikumar; Joel M Weinberg; Manjeri A Venkatachalam
Journal:  Am J Physiol Renal Physiol       Date:  2021-01-11
  9 in total

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