Literature DB >> 3349126

Behaviour of fibroblasts and epidermal cells cultivated on analogues of extracellular matrix.

C J Doillon1, A J Wasserman, R A Berg, F H Silver.   

Abstract

A porous collagen sponge can be used for supporting epidermal cells and fibroblasts in order to manufacture an artificial skin. Fibroblasts were grown on analogues of extracellular matrix containing collagen and glycosaminoglycans and/or glycoproteins. Cell replication, and also infiltration of fibroblasts, were enhanced by the presence of hyaluronic acid and/or fibronectin. Epidermal cells grown on a collagen sponge have been characterized by microscopic observations. Epidermal cells on the surface of the sponge showed an incomplete differentiation in comparison to normal skin; clumps of epidermal cells were found in the interior of the sponge. Epidermal cell replication was enhanced in the presence of collagen sponge seeded with fibroblasts.

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Year:  1988        PMID： 3349126     DOI： 10.1016/0142-9612(88)90077-4

Source DB:  PubMed          Journal:  Biomaterials        ISSN： 0142-9612            Impact factor:   12.479


  7 in total

1.  In vitro biocompatibility test for collagen-based dressings.

Authors:  M Balasubramani; M Babu; P K Sehgal
Journal:  In Vitro Cell Dev Biol Anim       Date:  1997-04       Impact factor: 2.723

2.  A novel artificial substrate for cell culture: effects of substrate flexibility/malleability on cell growth and morphology.

Authors:  H P Hohn; U Steih; H W Denker
Journal:  In Vitro Cell Dev Biol Anim       Date:  1995-01       Impact factor: 2.416

3.  Characterization of esterified hyaluronan-gelatin polymer composites suitable for chondrogenic differentiation of mesenchymal stem cells.

Authors:  Peter Angele; Rainer Müller; Detlef Schumann; Carsten Englert; Johannes Zellner; Brian Johnstone; Jung Yoo; Joachim Hammer; Johann Fierlbeck; Martin K Angele; Michael Nerlich; Richard Kujat
Journal:  J Biomed Mater Res A       Date:  2009-11       Impact factor: 4.396

4.  The influence of crosslinking agents and diamines on the pore size, morphology and the biological stability of collagen sponges and their effect on cell penetration through the sponge matrix.

Authors:  M McKegney; I Taggart; M H Grant
Journal:  J Mater Sci Mater Med       Date:  2001-09       Impact factor: 3.896

5.  [Use of biophysical techniques to evaluate the physiologic effects of injected hyaluronic acid].

Authors:  T Reuther; J Bayrhammer; M Kerscher
Journal:  Hautarzt       Date:  2007-12       Impact factor: 0.751

6.  Treatment of the ageing hand with dermal fillers.

Authors:  Ulrich Kühne; Matthias Imhof
Journal:  J Cutan Aesthet Surg       Date:  2012-07

7.  Difficult-to-heal wounds of mixed arterial/venous and venous etiology: a cost-effectiveness analysis of extracellular matrix.

Authors:  Marco Romanelli; Adrienne M Gilligan; Curtis R Waycaster; Valentina Dini
Journal:  Clinicoecon Outcomes Res       Date:  2016-05-04
  7 in total

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