Literature DB >> 33490116

The Relationship between Dialysis Metrics and Patient-Reported Cognition, Fatigue, and Physical Function.

Daniel A Sturgill1, Naveet Bal1, Sneha Nagavally2, Dawn F Wolfgram1.   

Abstract

INTRODUCTION: The impact of achieving hemodialysis laboratory and hemodynamic quality metrics on patient-reported outcomes (PROs) is unknown.
OBJECTIVE: To determine if meeting dialysis laboratory quality of care measures is associated with improved PROs.
METHODS: In this cross-sectional study, we measured the relationship between dialysis patients' Patient Reported Outcome Measurement Information System (PROMIS) scores and commonly used dialysis quality of care measures.
RESULTS: PROMIS surveys were administered to 92 dialysis patients. The mean ± SD scores demonstrated higher fatigue (55.0 ± 9.8) and lower physical function (37.9 ± 7.9) but similar cognition (50.3 ± 10.9) compared to general population normative scores of 50 ± 10. Dialysis patients meeting Kt/V goals had no better scores than those who did not. Meeting the hemoglobin (Hgb) value of ≥10 g/dL was associated with a lower fatigue score, but no difference in cognitive or physical function scores. Meeting the serum albumin goal of ≥4.0 mg/dL was associated with a higher physical function score but made no difference for cognitive function or fatigue score. As a continuous variable, a higher Hgb was associated with lower reported fatigue (HR -1.74 95%, CI [-3.09, -0.39]), but no other measures were associated with PRO scores when adjusted for demographics and comorbidities.
CONCLUSIONS: We found little association between measures currently used to assess the quality of dialysis care and PROs. Encouraging improved utilization of PROs and incorporating PROs into quality measurements might give a more robust assessment of quality of care. Future studies should assess the benefits of this approach.
Copyright © 2020 by S. Karger AG, Basel.

Entities:  

Keywords:  Dialysis; Fatigue; Function; PROMIS; Patient-reported outcome

Year:  2020        PMID: 33490116      PMCID: PMC7745663          DOI: 10.1159/000508919

Source DB:  PubMed          Journal:  Kidney Dis (Basel)        ISSN: 2296-9357


  28 in total

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Authors:  Jeffrey Perl; Laura M Dember; Joanne M Bargman; Teri Browne; David M Charytan; Jennifer E Flythe; LaTonya J Hickson; Adriana M Hung; Michel Jadoul; Timmy Chang Lee; Klemens B Meyer; Hamid Moradi; Tariq Shafi; Isaac Teitelbaum; Leslie P Wong; Christopher T Chan
Journal:  Clin J Am Soc Nephrol       Date:  2017-03-17       Impact factor: 8.237

2.  The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005-2008.

Authors:  David Cella; William Riley; Arthur Stone; Nan Rothrock; Bryce Reeve; Susan Yount; Dagmar Amtmann; Rita Bode; Daniel Buysse; Seung Choi; Karon Cook; Robert Devellis; Darren DeWalt; James F Fries; Richard Gershon; Elizabeth A Hahn; Jin-Shei Lai; Paul Pilkonis; Dennis Revicki; Matthias Rose; Kevin Weinfurt; Ron Hays
Journal:  J Clin Epidemiol       Date:  2010-08-04       Impact factor: 6.437

3.  Association of self-reported physical activity with laboratory markers of nutrition and inflammation: the Comprehensive Dialysis Study.

Authors:  Shuchi Anand; Glenn M Chertow; Kirsten L Johansen; Barbara Grimes; Manjula Kurella Tamura; Lorien S Dalrymple; George A Kaysen
Journal:  J Ren Nutr       Date:  2011-01-15       Impact factor: 3.655

4.  The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis.

Authors:  W F Owen; N L Lew; Y Liu; E G Lowrie; J M Lazarus
Journal:  N Engl J Med       Date:  1993-09-30       Impact factor: 91.245

5.  Validation of the Patient-Reported Outcomes Measurement Information System (PROMIS)-57 and -29 item short forms among kidney transplant recipients.

Authors:  Evan Tang; Oladapo Ekundayo; John Devin Peipert; Nathaniel Edwards; Aarushi Bansal; Candice Richardson; Susan J Bartlett; Doris Howell; Madeline Li; David Cella; Marta Novak; Istvan Mucsi
Journal:  Qual Life Res       Date:  2018-11-22       Impact factor: 4.147

6.  Cognitive impairment in hemodialysis patients is common.

Authors:  A M Murray; D E Tupper; D S Knopman; D T Gilbertson; S L Pederson; S Li; G E Smith; A K Hochhalter; A J Collins; R L Kane
Journal:  Neurology       Date:  2006-07-25       Impact factor: 9.910

7.  PROMIS measures of pain, fatigue, negative affect, physical function, and social function demonstrated clinical validity across a range of chronic conditions.

Authors:  Karon F Cook; Sally E Jensen; Benjamin D Schalet; Jennifer L Beaumont; Dagmar Amtmann; Susan Czajkowski; Darren A Dewalt; James F Fries; Paul A Pilkonis; Bryce B Reeve; Arthur A Stone; Kevin P Weinfurt; David Cella
Journal:  J Clin Epidemiol       Date:  2016-03-04       Impact factor: 6.437

8.  Health-related quality of life as a predictor of mortality and hospitalization: the Dialysis Outcomes and Practice Patterns Study (DOPPS).

Authors:  Donna L Mapes; Antonio Alberto Lopes; Sudtida Satayathum; Keith P McCullough; David A Goodkin; Francesco Locatelli; Shunichi Fukuhara; Eric W Young; Kiyoshi Kurokawa; Akira Saito; Jürgen Bommer; Robert A Wolfe; Philip J Held; Friedrich K Port
Journal:  Kidney Int       Date:  2003-07       Impact factor: 10.612

9.  Symptom burden, depression, and quality of life in chronic and end-stage kidney disease.

Authors:  Khaled Abdel-Kader; Mark L Unruh; Steven D Weisbord
Journal:  Clin J Am Soc Nephrol       Date:  2009-05-07       Impact factor: 8.237

10.  Effect of dialysis dose and membrane flux in maintenance hemodialysis.

Authors:  Garabed Eknoyan; Gerald J Beck; Alfred K Cheung; John T Daugirdas; Tom Greene; John W Kusek; Michael Allon; James Bailey; James A Delmez; Thomas A Depner; Johanna T Dwyer; Andrew S Levey; Nathan W Levin; Edgar Milford; Daniel B Ornt; Michael V Rocco; Gerald Schulman; Steve J Schwab; Brendan P Teehan; Robert Toto
Journal:  N Engl J Med       Date:  2002-12-19       Impact factor: 91.245

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  2 in total

1.  Correlation between Physical Activity and Psychological Distress in Patients Receiving Hemodialysis with Comorbidities: A Cross-Sectional Study.

Authors:  Yu-Hui Wu; Yu-Juei Hsu; Wen-Chii Tzeng
Journal:  Int J Environ Res Public Health       Date:  2022-03-26       Impact factor: 3.390

2.  Evaluation of PROMIS Preference Scoring System (PROPr) in Patients Undergoing Hemodialysis or Kidney Transplant.

Authors:  Jing Zhang; Barry Dewitt; Evan Tang; Daniel Breitner; Mohammed Saqib; Dan Li; Rabail Siddiqui; Nathaniel Edwards; John Devin Peipert; Ron D Hays; Janel Hanmer; Istvan Mucsi
Journal:  Clin J Am Soc Nephrol       Date:  2021-07-16       Impact factor: 10.614

  2 in total

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