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Literature DB >> 3349009

Ocular and cardiovascular response to topical carteolol 2% and timolol 0.5% in healthy volunteers.

Abstract

Ocular and cardiovascular effects of carteolol 2%, timolol 0.5%, and dummy eyedrops have been measured in a single dose double-blind crossover study in six healthy volunteers. Both drugs lowered intraocular pressure and reduced exercise-induced tachycardia. Neither produced a significant change in resting heart rate or blood pressure. The two agents appear comparable as regards ocular hypotensive and cardiovascular effects.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1988 PMID： 3349009 PMCID： PMC1041380 DOI： 10.1136/bjo.72.2.101

Source DB: PubMed Journal: Br J Ophthalmol ISSN： 0007-1161 Impact factor: 4.638

6 in total

1. Respiratory difficulties with betaxolol.

Authors: L S Harris; S H Greenstein; A F Bloom
Journal: Am J Ophthalmol Date: 1986-08-15 Impact factor: 5.258

2. A blind randomised cross-over trial comparing metipranolol 0.3% with timolol 0.25% in open-angle glaucoma: a pilot study.

Authors: K B Mills; G Wright
Journal: Br J Ophthalmol Date: 1986-01 Impact factor: 4.638

3. Adverse reactions from timolol administration.

Authors: E M Van Buskirk
Journal: Ophthalmology Date: 1980-05 Impact factor: 12.079

4. A double-masked comparison of betaxolol vs timolol in the treatment of open-angle glaucoma.

Authors: R C Allen; E Hertzmark; A M Walker; D L Epstein
Journal: Am J Ophthalmol Date: 1986-05-15 Impact factor: 5.258

5. Betaxolol in patients with glaucoma and asthma.

Authors: E M Van Buskirk; R N Weinreb; D P Berry; J S Lustgarten; S M Podos; M M Drake
Journal: Am J Ophthalmol Date: 1986-05-15 Impact factor: 5.258

6. Polymorphic hydroxylation of Debrisoquine in man.

Authors: A Mahgoub; J R Idle; L G Dring; R Lancaster; R L Smith
Journal: Lancet Date: 1977-09-17 Impact factor: 79.321

6 in total

10 in total

1. Topical timolol and serum lipoproteins.

Authors: J West; S Longstaff
Journal: Br J Ophthalmol Date: 1990-11 Impact factor: 4.638

2. Cardiac side effects of beta blocker eyedrops.

Authors: J L Jay
Journal: Br J Ophthalmol Date: 1988-03 Impact factor: 4.638

Review 3. Ocular carteolol. A review of its pharmacological properties, and therapeutic use in glaucoma and ocular hypertension.

Authors: P Chrisp; E M Sorkin
Journal: Drugs Aging Date: 1992 Jan-Feb Impact factor: 3.923

4. Cardiovascular responses to metipranolol and timolol eyedrops in healthy volunteers.

Authors: P J Bacon; D J Brazier; R Smith; S E Smith
Journal: Br J Clin Pharmacol Date: 1989-01 Impact factor: 4.335

Review 5. Ocular carteolol: a review of its use in the management of glaucoma and ocular hypertension.

Authors: Sheridan Henness; Tracy Swainston Harrison; Gillian M Keating
Journal: Drugs Aging Date: 2007 Impact factor: 3.923

Review 6. Ocular beta-blockers in glaucoma management. Clinical pharmacological aspects.

Authors: A M Brooks; W E Gillies
Journal: Drugs Aging Date: 1992 May-Jun Impact factor: 3.923

7. Apraclonidine hydrochloride: an evaluation of plasma concentrations, and a comparison of its intraocular pressure lowering and cardiovascular effects to timolol maleate.

Authors: A L Robin; A L Coleman
Journal: Trans Am Ophthalmol Soc Date: 1990