The Promises and Realities of Integration in Synthetic Biology: A View From Social Science.

Discussions about the responsible advancement of synthetic biology science are at fever pitch. Commentators from across the globe are calling for greater integrated science investments and more inclusive governance processes in the development and implementation of these potentially disruptive technologies. We take stock of the promises and realities of science integration by sharing our experiences of embarking on this very challenge in Australia. We conclude by offering suggestions for bringing about the enabling conditions for improved integration across the natural and social sciences. Four key actions are articulated to help pivot synthetic biology toward a more integrated scientific endeavor: (a) formalizing inclusivity from inception to project conclusion; (b) valuing differing philosophical positions as a strength rather than a barrier; (c) accepting that integration takes persistence and communication but is immensely rewarding; and (d) promoting meaningful interactions, such as pursuing joint opportunities, co-designing and co-publishing research. We argue that these actions are key enablers for realizing science integration in synthetic biology.