Literature DB >> 33489971

Multiple Schwannomas of the Median Nerve: A Case Report and Review of the Literature.

Mohamed Salar1, Marc B Kaye1.   

Abstract

INTRODUCTION: Schwannomas are rare benign tumors affecting the peripheral nerves. They can grow in clusters when associated with neurofibromatosis Type II or with schwannomatosis. Typically, patients present with a palpable painless mass. However, some patients, on the other hand, present with symptomatic lesions that resemble a focal nerve compression caused by the encapsulating nature of these tumors. Surgical excision is an excellent solution for solitary symptomatic lesions. However, multiple schwannomas affecting the same nerve add another level of complexity to the surgery since these secondary masses can be too small to be detected on physical examination. A high index of suspension for schwannomatosis complemented with magnetic resonance imaging (MRI) ensures a more efficient pre-operative workup that can save the patient potentially an additional visit to the operating room. CASE REPORT: This is a case of a 36-year-old right-handed female presented to our clinic with a several-years history of a painful mass in her forearm. On physical examination, she had a palpable painful mass that was Tinel positive with pain and paresthesia radiating distally over the median nerve distribution. A subsequent MRI scan showed a second smaller mass distally adjacent to the main lesion along with the median nerve, both appearing to be schwannomas of the median nerve. In this case report, we discuss the patient presentation, diagnostic workup and radiographic finding, surgical technique, and pathological findings in addition to a review of the literature regarding multiple schwannomas affecting the upper extremity.
CONCLUSION: Schwannomas are rare benign tumors affecting the peripheral nerves. Despite their solitary nature, a handful of cases are reported in the literature that describes multiple masses encapsulating the same nerve. MRI is utilized to allow proper pre-operative planning and more accurate localization of these tumors to avoid an unplanned return to the operating room. Copyright: © Indian Orthopaedic Research Group.

Entities:  

Keywords:  Multiple schwannomas; neurilemoma; schwannomatosis

Year:  2020        PMID: 33489971      PMCID: PMC7815672          DOI: 10.13107/jocr.2020.v10.i06.1876

Source DB:  PubMed          Journal:  J Orthop Case Rep        ISSN: 2250-0685


  11 in total

Review 1.  Schwannomas of the hand and wrist: long-term results and review of the literature.

Authors:  O Ozdemir; M H Ozsoy; C Kurt; E Coskunol; I Calli
Journal:  J Orthop Surg (Hong Kong)       Date:  2005-12       Impact factor: 1.118

2.  Benign encapsulated neurilemoma: a report of 76 cases.

Authors:  W G Whitaker; C Droulias
Journal:  Am Surg       Date:  1976-09       Impact factor: 0.688

3.  MRI of peripheral nerve lesions of the lower limbs.

Authors:  M C Lacour-Petit; P Lozeron; D Ducreux
Journal:  Neuroradiology       Date:  2003-02-19       Impact factor: 2.804

4.  Nerve tumours in the upper limb. A clinical review.

Authors:  B J Holdsworth
Journal:  J Hand Surg Br       Date:  1985-06

5.  Peroneal nerve ganglion cyst.

Authors:  R M Spillane; G J Whitman; F S Chew
Journal:  AJR Am J Roentgenol       Date:  1996-03       Impact factor: 3.959

6.  Neurilemmomas of the forearm and hand.

Authors:  G S Phalen
Journal:  Clin Orthop Relat Res       Date:  1976 Jan-Feb       Impact factor: 4.176

7.  Regional Multiplicity of a neurilemmoma.

Authors:  O A Hecht; A Hass
Journal:  Hand       Date:  1982-02

8.  Multiplicity of neurilemomas in the upper extremity.

Authors:  P S Barre; J W Shaffer; J R Carter; S H Lacey
Journal:  J Hand Surg Am       Date:  1987-03       Impact factor: 2.230

Review 9.  Multiple schwannomas of the median nerve: a case report and literature review.

Authors:  N Aslam; G Kerr
Journal:  Hand Surg       Date:  2003-12

10.  Multiple neurilemomas. A case report.

Authors:  K H Shin; S H Moon; J S Suh; J S Jahng
Journal:  Clin Orthop Relat Res       Date:  1998-12       Impact factor: 4.176

View more
  1 in total

1.  WP1066 induces cell death in a schwannomatosis patient-derived schwannoma cell line.

Authors:  Abdulrahman Allaf; Berta Victoria; Rosa Rosario; Carly Misztal; Sakir Humayun Gultekin; Christine T Dinh; Cristina Fernandez-Valle
Journal:  Cold Spring Harb Mol Case Stud       Date:  2022-06-22
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.