Literature DB >> 33489607

Emergent Repair of a Perforated Giant Duodenal Ulcer in a Patient With an Unmanaged Ulcer History.

Eli B Eisman1,2, Nicole C Jamieson2, Rashona A Moss3, Melina M Henderson4, Richard C Spinale2.   

Abstract

Giant duodenal ulcers (GDUs) are full-thickness disruptions of the gastrointestinal epithelium greater than 3cm in diameter. The significant size and disease chronicity lead to deleterious outcomes and high mortality risk if ulcer progression is not halted. While still prevalent in developing countries, GDUs are increasingly rare in industrialized nations. Here, we present the case of an 82-year-old woman with perforated GDU requiring emergent surgical intervention complicated by prior duodenal surgery requiring a previously unreported triple-layered omental patch. Discussion of this technique and novel approaches to GDU repair ensue.
Copyright © 2020, Eisman et al.

Entities:  

Keywords:  chronic ulcer; complicated peptic ulcer disease; duodenal ulceration; duodenal ulcers; gastrointestinal perforation; graham patch repair; perforated duodenal ulcer

Year:  2020        PMID: 33489607      PMCID: PMC7815296          DOI: 10.7759/cureus.12198

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  19 in total

1.  Commentary: Perforated giant duodenal ulcers: what is the best treatment?

Authors:  Mark A Malangoni
Journal:  Am J Surg       Date:  2009-09       Impact factor: 2.565

2.  Superiority of lansoprazole vs ranitidine in healing nonsteroidal anti-inflammatory drug-associated gastric ulcers: results of a double-blind, randomized, multicenter study. NSAID-Associated Gastric Ulcer Study Group.

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Journal:  Br J Surg       Date:  1993-01       Impact factor: 6.939

4.  Use of omeprazole in the management of giant duodenal ulcer: results of a prospective study.

Authors:  D R Fischer; M S Nussbaum; T A Pritts; N H Gilinsky; R E Weesner; S P Martin; R A Giannella
Journal:  Surgery       Date:  1999-10       Impact factor: 3.982

5.  Omental plugging for large-sized duodenal peptic perforations: A prospective randomized study of 100 patients.

Authors:  Kalpesh Jani; A K Saxena; Rasik Vaghasia
Journal:  South Med J       Date:  2006-05       Impact factor: 0.954

6.  Risk factors predicting operative mortality in perforated peptic ulcer disease.

Authors:  V Rajesh; S Sarath Chandra; S Robinson Smile
Journal:  Trop Gastroenterol       Date:  2003 Jul-Sep

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Authors:  H M Al Freihi
Journal:  Saudi J Gastroenterol       Date:  1995-05       Impact factor: 2.485

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Authors:  T W Klamer; M M Mahr
Journal:  Am J Surg       Date:  1978-06       Impact factor: 2.565

Review 9.  Pathogenesis and therapy of gastric and duodenal ulcer disease.

Authors:  Akiko Shiotani; David Y Graham
Journal:  Med Clin North Am       Date:  2002-11       Impact factor: 5.456

10.  The management of large perforations of duodenal ulcers.

Authors:  Sanjay Gupta; Robin Kaushik; Rajeev Sharma; Ashok Attri
Journal:  BMC Surg       Date:  2005-06-25       Impact factor: 2.102

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  1 in total

1.  Outcomes of surgical management of peptic ulcer perforation using the falciform ligament: A cross-sectional study at a single centre in Vietnam.

Authors:  Tran Que Son; Tran Hieu Hoc; Tran Thu Huong; Vu Duc Long; Tran Thanh Tung; Nguyen Chien Quyet; Lun Panha; Nguyen Van Chi
Journal:  Ann Med Surg (Lond)       Date:  2021-06-16
  1 in total

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