| Literature DB >> 33489498 |
Erick Martín Páez Hernández1, Luis Abraham Zúñiga Vázquez2, Aldo Edyair Jiménez Herevia1, Diego Hinojosa Ugarte1, Enrique Obregón Moreno1.
Abstract
Chloromas are an atypical cellular infiltrate of immature granulocytic cells that can occur specially in patients with acute myelogenous leukemia (AML), but can be present in nonleukemic patients. Its clinical course will be dependent on its size and location, from asymptomatic to simulating a malignant gastrointestinal neoplasia. Definitive diagnosis is made upon an immunoprofile that is similar to that present in the blasts and precursor cells of acute myeloid leukemia. Endoscopic and CT images are variable being only part of the protocol panel. Treatment is the same as to AML, but surgery and radiation must be used in order to maintain low relapse and better overall survival.Entities:
Keywords: chloroma; granulocytic sarcoma; intestinal chloroma; myeloid sarcoma
Year: 2020 PMID: 33489498 PMCID: PMC7805528 DOI: 10.7759/cureus.12080
Source DB: PubMed Journal: Cureus ISSN: 2168-8184