Literature DB >> 33488935

Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine.

Dengyu Yang1, Tiancheng Wang1, Miao Long1, Peng Li1.   

Abstract

Quercetin is a flavonoid compound widely present in plants and exhibits a variety of biological activities. Research on quercetin has shown its potential for medical application. In this research, we elucidate its antioxidant mechanism and the broad-spectrum antibacterial and antiparasite properties; summarise its potential application in antioncology and cardiovascular protection and anti-immunosuppression treatment; and demonstrate its ability to alleviate the toxicity of mycotoxins. This research is expected to offer some insights and inspirations for the further study of quercetin, its properties, and the scientific basis for its better application in clinical practice.
Copyright © 2020 Dengyu Yang et al.

Entities:  

Year:  2020        PMID： 33488935      PMCID： PMC7790550          DOI： 10.1155/2020/8825387

Source DB:  PubMed          Journal:  Oxid Med Cell Longev        ISSN： 1942-0994            Impact factor:   6.543


  125 in total

1.  Quercetin and rutin as potential agents antifungal against Cryptococcus spp.

Authors:  V M Oliveira; E Carraro; M E Auler; N M Khalil
Journal:  Braz J Biol       Date:  2016-05-06       Impact factor: 1.651

2.  Quercetin attenuates chronic ethanol hepatotoxicity: implication of "free" iron uptake and release.

Authors:  Yuhan Tang; Yanyan Li; Haiyan Yu; Chao Gao; Liang Liu; Mingyou Xing; Liegang Liu; Ping Yao
Journal:  Food Chem Toxicol       Date:  2014-02-22       Impact factor: 6.023

3.  Hepatoprotective and free radical scavenging actions of quercetin nanoparticles on aflatoxin B1-induced liver damage: in vitro/in vivo studies.

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Journal:  Artif Cells Nanomed Biotechnol       Date:  2017-04-20       Impact factor: 5.678

Review 4.  Anti-inflammatory and anti-allergic properties of flavonoids.

Authors:  M Gábor
Journal:  Prog Clin Biol Res       Date:  1986

5.  DPPH, ABTS free radical scavenging, antibacterial and phytochemical evaluation of crude methanolic extract and subsequent fractions of Chenopodium botrys aerial parts.

Authors:  Farhat Ullah; Naveed Iqbal; Muhammad Ayaz; Abdul Sadiq; Ihsan Ullah; Sajjad Ahmad; Muhammad Imran
Journal:  Pak J Pharm Sci       Date:  2017-05       Impact factor: 0.684

Review 6.  Cardiovascular Disease: A Target for the Pharmacological Effects of Quercetin.

Authors:  Juan Guillermo Gormaz; Sebastian Quintremil; Ramon Rodrigo
Journal:  Curr Top Med Chem       Date:  2015       Impact factor: 3.295

7.  Resveratrol and quercetin, two natural polyphenols, reduce apoptotic neuronal cell death induced by neuroinflammation.

Authors:  Genevieve Bureau; Fanny Longpré; M-G Martinoli
Journal:  J Neurosci Res       Date:  2008-02-01       Impact factor: 4.164

8.  Effect of Ginkgo biloba extract on rat hepatic microsomal CYP1A activity: role of ginkgolides, bilobalide, and flavonols.

Authors:  I fan Kuo; Jie Chen; Thomas K H Chang
Journal:  Can J Physiol Pharmacol       Date:  2004-01       Impact factor: 2.273

9.  High-performance therapeutic quercetin-doped adhesive for adhesive-dentin interfaces.

Authors:  Hongye Yang; Kang Li; Huiyi Yan; Siying Liu; Yake Wang; Cui Huang
Journal:  Sci Rep       Date:  2017-08-15       Impact factor: 4.379

10.  Quercetin protects rats from catheter-related Staphylococcus aureus infections by inhibiting coagulase activity.

Authors:  Lin Wang; BangBang Li; Xiaosa Si; Xingyuan Liu; Xuming Deng; Xiaodi Niu; Yingli Jin; Dacheng Wang; Jianfeng Wang
Journal:  J Cell Mol Med       Date:  2019-05-15       Impact factor: 5.310
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  34 in total

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Journal:  Drug Des Devel Ther       Date:  2022-01-06       Impact factor: 4.162

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Authors:  Yunxin Zhou; Fan Zhang; Junying Ding
Journal:  Immune Netw       Date:  2022-06-20       Impact factor: 5.851

3.  Discovery of Quercetin and Its Analogs as Potent OXA-48 Beta-Lactamase Inhibitors.

Authors:  Yuejuan Zhang; Cheng Chen; Bin Cheng; Lei Gao; Chuan Qin; Lixia Zhang; Xu Zhang; Jun Wang; Yi Wan
Journal:  Front Pharmacol       Date:  2022-06-22       Impact factor: 5.988

Review 4.  Antimicrobial Activity of Quercetin: An Approach to Its Mechanistic Principle.

Authors:  Thi Lan Anh Nguyen; Debanjana Bhattacharya
Journal:  Molecules       Date:  2022-04-12       Impact factor: 4.927

5.  Botanical Interventions to Improve Glucose Control and Options for Diabetes Therapy.

Authors:  Peter Smoak; Susan J Burke; J Jason Collier
Journal:  SN Compr Clin Med       Date:  2021-08-15

6.  Hydrogel Containing Borassus flabellifer L. Male Flower Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity.

Authors:  Prakairat Tunit; Phanit Thammarat; Siriporn Okonogi; Chuda Chittasupho
Journal:  Gels       Date:  2022-02-17

Review 7.  Potential Implications of Quercetin in Autoimmune Diseases.

Authors:  Pan Shen; Weiji Lin; Xuan Deng; Xin Ba; Liang Han; Zhe Chen; Kai Qin; Ying Huang; Shenghao Tu
Journal:  Front Immunol       Date:  2021-06-23       Impact factor: 7.561

Review 8.  Neuropharmacological Effects of Quercetin: A Literature-Based Review.

Authors:  Md Shahazul Islam; Cristina Quispe; Rajib Hossain; Muhammad Torequl Islam; Ahmed Al-Harrasi; Ahmed Al-Rawahi; Miquel Martorell; Assem Mamurova; Ainur Seilkhan; Nazgul Altybaeva; Bagila Abdullayeva; Anca Oana Docea; Daniela Calina; Javad Sharifi-Rad
Journal:  Front Pharmacol       Date:  2021-06-17       Impact factor: 5.810

9.  Lipid Nanocarriers-Loaded Nanocomposite as a Suitable Platform to Release Antibacterial and Antioxidant Agents for Immediate Dental Implant Placement Restorative Treatment.

Authors:  Giuseppe Angellotti; Alessandro Presentato; Denise Murgia; Giulia Di Prima; Fabio D'Agostino; Amalia Giulia Scarpaci; Maria Cristina D'Oca; Rosa Alduina; Giuseppina Campisi; Viviana De Caro
Journal:  Pharmaceutics       Date:  2021-12-03       Impact factor: 6.321

10.  Quercetin protects islet β-cells from oxidation-induced apoptosis via Sirt3 in T2DM.

Authors:  Jian-Yun Wang; Ya-Xing Nie; Bing-Zheng Dong; Zhi-Chen Cai; Xuan-Kai Zeng; Lei Du; Xia Zhu; Xiao-Xing Yin
Journal:  Iran J Basic Med Sci       Date:  2021-05       Impact factor: 2.699
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