Literature DB >> 33488919

Dermatologist Use of Intralesional Triamcinolone in the Treatment of Acne.

Tara Gallagher1,2, Mark Taliercio1,2, John K Nia1,2, Peter W Hashim1,2, Joshua A Zeichner1,2.   

Abstract

OBJECTIVE: Despite common administration of intralesional triamcinolone to acne lesions, there is little published data or consensus on best practices. This study aimed to evaluate specific characteristics of intralesional triamcinolone for acne among various dermatology healthcare professionals.
DESIGN: One hundred participants (82 attending physicians, 9 physician assistants, 8 other healthcare professionals, and 1 unidentified) from private practices and academic centers completed a 10-question survey to assess specific characteristics of intralesional triamcinolone injections, including frequency, indication, depth of injection, concentration, volume, as development of adverse events.
RESULTS: The most common reported concentration of intralesional triamcinolone was 2.5mg/mL (52.5%). The most frequently used volume injected was 0.05mL (42.3%). In total, 61.6 percent of those surveyed answered that they inject into the center of the lesion. Additionally, 50.5 percent of respondents counsel patients on potential adverse effects of hypopigmentation and atrophy before every injection. The majority of respondents (88.8%) reported that less than one percent of their patients returned for adverse events resulting from triamcinolone usage, and 48.4 percent reported that atrophy lasted over six months (48.4%).
CONCLUSION: The data collected from this study can offer guidance on best practices in administering intralesional kenalog to patients. While consistency exists for the concentration of triamcinolone used, there was significant discordance in the volumes and depth of triamcinolone injection. Observed skin atrophy rates are extremely low, but they are long lasting when it occurred. We can use these data to refine our treatment techniques as well as improve treatment outcomes and patient satisfaction.
Copyright © 2020. Matrix Medical Communications. All rights reserved.

Entities:  

Keywords:  Triamcinolone; acne; corticosteroids; cyst; inflammatory papule; injection

Year:  2020        PMID: 33488919      PMCID: PMC7819588     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  12 in total

1.  Intralesional injections of triamcinolone. Effects of different concentrations on psoriatic lesions.

Authors:  H PARISER; P F MURRAY
Journal:  Arch Dermatol       Date:  1963-02

2.  Localized involutional lipoatrophy: a clinicopathologic study of 16 patients.

Authors:  P R Dahl; M J Zalla; R K Winkelmann
Journal:  J Am Acad Dermatol       Date:  1996-10       Impact factor: 11.527

3.  Branch-shaped Cutaneous Hypopigmentation and Atrophy after Intralesional Triamcinolone Injection.

Authors:  Woo Sun Jang; Juhee Park; Kwang Ho Yoo; Tae Young Han; Kapsok Li; Seong Jun Seo; Chang Kwun Hong
Journal:  Ann Dermatol       Date:  2011-02-28       Impact factor: 1.444

4.  Treatment of local, persistent cutaneous atrophy following corticosteroid injection with normal saline infiltration.

Authors:  Peter R Shumaker; Jaggi Rao; Mitchel P Goldman
Journal:  Dermatol Surg       Date:  2005-10       Impact factor: 3.398

Review 5.  Benefits and risks of intralesional corticosteroid injection in the treatment of dermatological diseases.

Authors:  A Firooz; Z Tehranchi-Nia; A R Ahmed
Journal:  Clin Exp Dermatol       Date:  1995-09       Impact factor: 3.470

6.  Intralesional Injection of Triamcinolone Acetonide for Subcutaneous Lipoma causing Musculoskeletal and Neurologic Symptoms.

Authors:  William A Hayward; Wilmer L Sibbitt; Randy R Sibbitt; Maheswari Muruganandam; Noelle A Rolle; Monthida Fangtham; N Suzanne Emil; Scarlett K Kettwich
Journal:  J Clin Aesthet Dermatol       Date:  2018-05-01

7.  Subcutaneous Lipoatrophy and Skin Depigmentation Secondary to TMJ Intra-Articular Corticosteroid Injection.

Authors:  Nicolás Patricio Skármeta; Fernando Ariel Hormazábal; Juan Alvarado; Ana Maria Rodriguez
Journal:  J Oral Maxillofac Surg       Date:  2017-08-05       Impact factor: 1.895

Review 8.  Recent developments in the use of intralesional injections keloid treatment.

Authors:  Aurelia Trisliana Perdanasari; Davide Lazzeri; Weijie Su; Wenjing Xi; Zhang Zheng; Li Ke; Peiru Min; Shaoqing Feng; Yi Xin Zhang; Paolo Persichetti
Journal:  Arch Plast Surg       Date:  2014-11-03

9.  Successful treatment of lipoatrophy with normal saline.

Authors:  Samantha L Margulies; Andrea Morris
Journal:  JAAD Case Rep       Date:  2015-11-25

10.  Intralesional Treatment With 5-Fluorouracil and Steroid Improves Allergic Contact Dermatitis Without Causing Skin Atrophy and Rebound Lesions.

Authors:  Xiangming Chen; Guojiang Wang; Qingwen Zeng; Haiqing Zhang; Yang Hu; Aihua Yu; Ting Li
Journal:  Dermatitis       Date:  2017 May/Jun       Impact factor: 4.845

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  1 in total

Review 1.  Dermatology: how to manage acne vulgaris.

Authors:  Alexander Kc Leung; Benjamin Barankin; Joseph M Lam; Kin Fon Leong; Kam Lun Hon
Journal:  Drugs Context       Date:  2021-10-11
  1 in total

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