Literature DB >> 33488305

Thoughts on a Unified Theory of Disease.

Joseph Pizzorno.   

Abstract

Humans suffer the highest burden of chronic disease in every age group ever in human history. Why? While many theories have been proposed, presented here are thoughts on a unified theory of disease to understand causes and provide guidance for health restoration and disease prevention. My thesis is that the combination of high and increasing body load of heavy metals, meta-metals and persistent and non-persistent environmental chemicals; multiple nutrient deficiencies and insufficiencies and loss of "unimportant" molecules from the food supply; dis-synchronization with the environment; and genetic susceptibility combine to disrupt physiology and cause disease.
Copyright © 2020 InnoVision Professional Media Inc.

Entities:  

Year:  2020        PMID: 33488305      PMCID: PMC7819492     

Source DB:  PubMed          Journal:  Integr Med (Encinitas)        ISSN: 1546-993X


  12 in total

Review 1.  A study on the mineral depletion of the foods available to us as a nation over the period 1940 to 1991.

Authors:  David Thomas
Journal:  Nutr Health       Date:  2003

Review 2.  Crosstalk between xenobiotics metabolism and circadian clock.

Authors:  Thierry Claudel; Gaspard Cretenet; Anne Saumet; Frédéric Gachon
Journal:  FEBS Lett       Date:  2007-04-17       Impact factor: 4.124

3.  Plant metabolites and nutritional quality of vegetables.

Authors:  N Hounsome; B Hounsome; D Tomos; G Edwards-Jones
Journal:  J Food Sci       Date:  2008-05       Impact factor: 3.167

Review 4.  The uptake and bioaccumulation of heavy metals by food plants, their effects on plants nutrients, and associated health risk: a review.

Authors:  Anwarzeb Khan; Sardar Khan; Muhammad Amjad Khan; Zahir Qamar; Muhammad Waqas
Journal:  Environ Sci Pollut Res Int       Date:  2015-07-22       Impact factor: 4.223

5.  Down-regulation of cytochrome P450 1A1 by monomethylarsonous acid in human HepG2 cells.

Authors:  Osama H Elshenawy; Ghada Abdelhamid; Anatoly A Soshilov; Michael S Denison; Ayman O S El-Kadi
Journal:  Toxicol Lett       Date:  2017-02-09       Impact factor: 4.372

6.  Arsenic exposure and cancer mortality in a US-based prospective cohort: the strong heart study.

Authors:  Esther García-Esquinas; Marina Pollán; Jason G Umans; Kevin A Francesconi; Walter Goessler; Eliseo Guallar; Barbara Howard; John Farley; Lyle G Best; Ana Navas-Acien
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2013-10-17       Impact factor: 4.254

7.  Toxicological responses on cytochrome P450 and metabolic transferases in liver of goldfish (Carassius auratus) exposed to lead and paraquat.

Authors:  Xiaoming Xu; Zhaojie Cui; Xinlei Wang; Xixin Wang; Su Zhang
Journal:  Ecotoxicol Environ Saf       Date:  2018-01-30       Impact factor: 6.291

8.  Low-level lead exposure and mortality in US adults: a population-based cohort study.

Authors:  Bruce P Lanphear; Stephen Rauch; Peggy Auinger; Ryan W Allen; Richard W Hornung
Journal:  Lancet Public Health       Date:  2018-03-12

9.  Multivitamin/mineral supplement contribution to micronutrient intakes in the United States, 2007-2010.

Authors:  Taylor C Wallace; Michael McBurney; Victor L Fulgoni
Journal:  J Am Coll Nutr       Date:  2014       Impact factor: 3.169

10.  Arsenic in Drinking Water and Mortality for Cancer and Chronic Diseases in Central Italy, 1990-2010.

Authors:  Daniela D'Ippoliti; Enrica Santelli; Manuela De Sario; Matteo Scortichini; Marina Davoli; Paola Michelozzi
Journal:  PLoS One       Date:  2015-09-18       Impact factor: 3.240

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