Literature DB >> 3348821

Identification of brain lesions in neuropsychiatric systemic lupus erythematosus by magnetic resonance scanning.

W J McCune1, A MacGuire, A Aisen, S Gebarski.   

Abstract

Cranial magnetic resonance imaging in 28 systemic lupus erythematosus patients who had experienced 30 acute neuropsychiatric events showed focal brain lesions in 16 of 30 events (53%) and low brain volume (atrophy) in 20 of 30 events (67%). Definite focal lesions were significantly more frequent in patients with clinically localized neurologic deficits (8 of 8, 100%), or seizures (5 of 6, 83%) than in patients without such localizing signs (3 of 16, 19%). Many of these lesions were occult on intravenous contrast-enhanced x-ray computed tomography. In 2 patients, lesions in gray matter resolved within 2 or 3 weeks, in association with clinical improvement. Magnetic resonance imaging is an important technique for detecting the extent of brain injury in cerebral lupus.

Entities:  

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Year:  1988        PMID： 3348821     DOI： 10.1002/art.1780310202

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN： 0004-3591


  20 in total

1.  Abnormal brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus.

Authors:  Gerlof P Th Bosma; Tom W J Huizinga; Simon P Mooijaart; Mark A Van Buchem
Journal:  AJNR Am J Neuroradiol       Date:  2003-05       Impact factor: 3.825

2.  A Case of Mania in a Patient with Systemic Lupus Erythematosus: Can Its Inflammatory Pathogenesis be Applied to Primary Mood Disorders?

Authors:  David R Spiegel; Lindsay Holtz; Kokil Chopra
Journal:  Psychiatry (Edgmont)       Date:  2010-04

3.  Raised monocyte chemotactic protein-1 (MCP-1)/CCL2 in cerebrospinal fluid of patients with neuropsychiatric lupus.

Authors:  N Iikuni; H Okamoto; T Yoshio; E Sato; S Kamitsuji; T Iwamoto; S Momohara; A Taniguchi; H Yamanaka; S Minota; N Kamatani
Journal:  Ann Rheum Dis       Date:  2006-02       Impact factor: 19.103

4.  Neuroimaging in chronic fatigue syndrome.

Authors:  H Cope; A S David
Journal:  J Neurol Neurosurg Psychiatry       Date:  1996-05       Impact factor: 10.154

5.  Correlation of neurocognitive function and brain lesion load on magnetic resonance imaging in systemic lupus erythematosus.

Authors:  Paola C Roldan; Rex E Jung; Wilmer L Sibbitt; Clifford R Qualls; Ranee A Flores; Carlos A Roldan
Journal:  Rheumatol Int       Date:  2018-06-13       Impact factor: 2.631

6.  Markers of acute neuropsychiatric systemic lupus erythematosus: a multidisciplinary evaluation.

Authors:  Essam A Abda; Zahraa I Selim; Moustafa E M Radwan; Nagham M Mahmoud; Omar M Herdan; Khalid A Mohamad; Sherifa A Hamed
Journal:  Rheumatol Int       Date:  2012-10-12       Impact factor: 2.631

7.  Cortical thickness and subcortical gray matter reductions in neuropsychiatric systemic lupus erythematosus.

Authors:  Rex E Jung; Judith M Segall; Rachael G Grazioplene; Clifford Qualls; Wilmer L Sibbitt; Carlos A Roldan
Journal:  PLoS One       Date:  2010-03-24       Impact factor: 3.240

8.  Magnetic resonance imaging and brain histopathology in neuropsychiatric systemic lupus erythematosus.

Authors:  Wilmer L Sibbitt; William M Brooks; Mario Kornfeld; Blaine L Hart; Arthur D Bankhurst; Carlos A Roldan
Journal:  Semin Arthritis Rheum       Date:  2009-10-31       Impact factor: 5.532

9.  Brain single-photon emission tomography with 99mTc-HMPAO in neuropsychiatric systemic lupus erythematosus: relations with EEG and MRI findings and clinical manifestations.

Authors:  P Colamussi; M Giganti; C Cittanti; L Dovigo; F Trotta; M R Tola; R Tamarozzi; G Lucignani; A Piffanelli
Journal:  Eur J Nucl Med       Date:  1995-01

10.  Abnormalities of magnetic resonance imaging of the central nervous system in patients with systemic lupus erythematosus correlate with disease severity.

Authors:  A Cauli; C Montaldo; M T Peltz; P Nurchis; G Sanna; P Garau; R Pala; G Passiu; A Mathieu
Journal:  Clin Rheumatol       Date:  1994-12       Impact factor: 2.980
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