Sanjay Kumar Dhar1, K Raji2, Shankar Sandeep3. 1. Classified Specialist (Ophthalmology/ Paediatric Ophthalmology & Squint), Army Hospital (R&R), Delhi Cantt, 110010, India. 2. Senior Advisor, (Ophthalmology & VR Surgery), Army Hospital (R&R), Delhi Cantt, 110010, India. 3. Commandant, Military Hospital Wellington, Tamil Nadu, 643231, India.
Abstract
BACKGROUND: Glaucoma is an important and common optic neuropathy characterized by progressive loss of retinal ganglion cells and associated morphological changes to the optic nerve and retinal nerve fiber layer (RNFL). The most common assessment of visual function in glaucoma uses perimetric measurements of visual sensitivity. Only few studies have evaluated the binocular function in patients with glaucoma. This study was taken up to establish the correlation of RNFL thickness, in glaucoma, with near and distance stereopsis. METHODS: This pilot, cross-sectional observational study included 100 diagnosed cases of glaucoma and 100 normal participants as controls, studied over a period of one year. The records of all the participants were checked, and only established cases of glaucoma after fulfilling the inclusion and exclusion criteria were included. Analysis of the RNFL using spectral-domain optical coherence tomography was carried out. All the participants were thereafter evaluated for stereoacuity by near (at 40 inches) and distance (at 3 meter) Randot stereoacuity charts. RESULTS: There was a negative correlation between the RNFL thickness and the absolute value of streoacuity (-0.303 for distance versus -0.101 for near in cases and -0.308 for distance and -0.416 for near in control group), decreasing the actual functional stereoacuity, therefore the cases with lower RNFL thickness had lower stereoacuity both for distance and near, however it was statistically significant only for distance (p=0.002). CONCLUSION: Functional aspects, such as stereoacuity, may also be affected in the glaucoma because of decrease in RNFL thickness. Therefore, binocular status should also be evaluated in cases of glaucoma.
BACKGROUND: Glaucoma is an important and common optic neuropathy characterized by progressive loss of retinal ganglion cells and associated morphological changes to the optic nerve and retinal nerve fiber layer (RNFL). The most common assessment of visual function in glaucoma uses perimetric measurements of visual sensitivity. Only few studies have evaluated the binocular function in patients with glaucoma. This study was taken up to establish the correlation of RNFL thickness, in glaucoma, with near and distance stereopsis. METHODS: This pilot, cross-sectional observational study included 100 diagnosed cases of glaucoma and 100 normal participants as controls, studied over a period of one year. The records of all the participants were checked, and only established cases of glaucoma after fulfilling the inclusion and exclusion criteria were included. Analysis of the RNFL using spectral-domain optical coherence tomography was carried out. All the participants were thereafter evaluated for stereoacuity by near (at 40 inches) and distance (at 3 meter) Randot stereoacuity charts. RESULTS: There was a negative correlation between the RNFL thickness and the absolute value of streoacuity (-0.303 for distance versus -0.101 for near in cases and -0.308 for distance and -0.416 for near in control group), decreasing the actual functional stereoacuity, therefore the cases with lower RNFL thickness had lower stereoacuity both for distance and near, however it was statistically significant only for distance (p=0.002). CONCLUSION: Functional aspects, such as stereoacuity, may also be affected in the glaucoma because of decrease in RNFL thickness. Therefore, binocular status should also be evaluated in cases of glaucoma.
Authors: Alberto O González-García; Gianmarco Vizzeri; Christopher Bowd; Felipe A Medeiros; Linda M Zangwill; Robert N Weinreb Journal: Am J Ophthalmol Date: 2009-03-09 Impact factor: 5.258
Authors: Rajul S Parikh; Shefali Parikh; G Chandra Sekhar; Rajesh S Kumar; S Prabakaran; J Ganesh Babu; Ravi Thomas Journal: Ophthalmology Date: 2007-06-11 Impact factor: 12.079
Authors: Christopher Kai-Shun Leung; Carol Yim-Lui Cheung; Robert N Weinreb; Quanliang Qiu; Shu Liu; Haitao Li; Guihua Xu; Ning Fan; Lina Huang; Chi-Pui Pang; Dennis Shun Chiu Lam Journal: Ophthalmology Date: 2009-05-22 Impact factor: 12.079