Literature DB >> 3348781

Phosphorylation of platelet actin binding protein protects against proteolysis by calcium dependent sulfhydryl protease.

Z Zhang1, J Lawrence, A Stracher.   

Abstract

When Actin Binding Protein (ABP) isolated from human blood platelets is phosphorylated in vitro with a cyclic AMP dependent kinase it becomes resistant to proteolysis by the Calcium Dependent Sulfhydryl Protease (CDSP). This protection against proteolytic cleavage is specific for CDSP since phosphorylation of ABP does not protect against proteolysis by trypsin, papain and thermolysin. Thus, there appears to be a distinct phosphorylation site on the ABP molecule which is essential for regulating the initial proteolytic degradation of ABP by CDSP.

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Year:  1988        PMID： 3348781     DOI： 10.1016/0006-291x(88)90601-8

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  6 in total

1.  Phosphoproteomic profiling of myofibrillar and sarcoplasmic proteins of muscle in response to salting.

Authors:  Caixia Zhang; Zhenyu Wang; Zheng Li; Qingwu Shen; Lijuan Chen; Lingling Gao; Dequan Zhang
Journal:  Food Sci Biotechnol       Date:  2016-08-31       Impact factor: 2.391

2.  Decreased susceptibility of a 70-kDa protein to cathepsin L after phosphorylation by protein kinase C.

Authors:  S Laumas; M Abdel-Ghany; K Leister; R Resnick; A Kandrach; E Racker
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

Review 3.  The actin cytoskeleton in endothelial cell phenotypes.

Authors:  Nutan Prasain; Troy Stevens
Journal:  Microvasc Res       Date:  2008-10-26       Impact factor: 3.514

4.  Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring.

Authors:  J B Gorlin; R Yamin; S Egan; M Stewart; T P Stossel; D J Kwiatkowski; J H Hartwig
Journal:  J Cell Biol       Date:  1990-09       Impact factor: 10.539

5.  Filamin is required for ring canal assembly and actin organization during Drosophila oogenesis.

Authors:  M G Li; M Serr; K Edwards; S Ludmann; D Yamamoto; L G Tilney; C M Field; T S Hays
Journal:  J Cell Biol       Date:  1999-09-06       Impact factor: 10.539

6.  The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts.

Authors:  M Reinhard; M Halbrügge; U Scheer; C Wiegand; B M Jockusch; U Walter
Journal:  EMBO J       Date:  1992-06       Impact factor: 11.598
  6 in total

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