Literature DB >> 33487650

Correlation between Medication Administration-Related Errors in Patients with Parkinson Disease and Timing of Pharmacy-Led Best Possible Medication Histories.

Emily Cowley1, Michael R Miller2, Charles Yin3, Lynne Kelly4.   

Abstract

BACKGROUND: Poor prescribing and incomplete medication administration have been linked to increased lengths of hospitalization for patients with Parkinson disease. The Institute for Safe Medication Practices (ISMP) has recommended that patients with Parkinson disease receive a pharmacy consultation within 2 h of admission to hospital.
OBJECTIVES: To examine whether the time for a pharmacy team member to obtain a best possible medication history (BPMH) was associated with administration-related medication errors. The primary outcome was the proportion of doses with a medication error during a patient's admission in relation to the time to completion of the initial BPMH by a registered pharmacist (RPh) or registered pharmacy technician (RPhT). The secondary objective was to compare the proportion of doses with a medication error in relation to whether the BPMH was completed by an RPh or an RPhT.
METHODS: This retrospective chart review involved patients with Parkinson disease who were admitted to the medicine services at London Health Sciences Centre from September 30, 2014, to September 30, 2018. Patients were included if they had Parkinson disease and a medication regimen that included levodopa-carbidopa. For all patients, an RPhT or RPh conducted the initial BPMH or updated the BPMH. Pearson correlation analysis was used to determine whether a correlation existed between administration-related errors and completion of the BPMH by a pharmacy staff member.
RESULTS: A total of 84 patients with 104 admissions were included. There was no significant correlation between the time to completion of the initial BPMH by a pharmacy team member and the proportion of doses with medication errors (p = 0.32). Although RPhTs completed the BPMHs more quickly than RPhs (p < 0.001), there was no significant difference between pharmacy team members in terms of the proportion of doses with medication errors (p = 0.86).
CONCLUSIONS: Completing a BPMH within 2 h of a patient's admission, as per the ISMP recommendation, is unlikely to affect administration-related medication errors, given that no correlation was identified. Expediting BPMH without addressing other factors is insufficient, and initiatives are required to improve the medication administration process. 2021 Canadian Society of Hospital Pharmacists. All content in the Canadian Journal of Hospital Pharmacy is copyrighted by the Canadian Society of Hospital Pharmacy. In submitting their manuscripts, the authors transfer, assign, and otherwise convey all copyright ownership to CSHP.

Entities:  

Keywords:  Parkinson disease; best possible medication history; erreur de médication; maladie de Parkinson; medication error; meilleur schéma thérapeutique possible

Year:  2021        PMID: 33487650      PMCID: PMC7801329     

Source DB:  PubMed          Journal:  Can J Hosp Pharm        ISSN: 0008-4123


  7 in total

1.  Levodopa and the progression of Parkinson's disease.

Authors:  Stanley Fahn; David Oakes; Ira Shoulson; Karl Kieburtz; Alice Rudolph; Anthony Lang; C Warren Olanow; Caroline Tanner; Kenneth Marek
Journal:  N Engl J Med       Date:  2004-12-09       Impact factor: 91.245

2.  Best possible medication history in the emergency department: comparing pharmacy technicians and pharmacists.

Authors:  Rochelle Johnston; Lauza Saulnier; Odette Gould
Journal:  Can J Hosp Pharm       Date:  2010-09

3.  Medication errors in Parkinson's disease inpatients in the Basque Country.

Authors:  Unax Lertxundi; Arantxa Isla; María Ángeles Solinís; Saioa Domingo- Echaburu; Rafael Hernandez; Javier Peral-Aguirregoitia; Juan Medrano; Juan Carlos García-Moncó
Journal:  Parkinsonism Relat Disord       Date:  2016-12-31       Impact factor: 4.891

4.  Delayed Administration and Contraindicated Drugs Place Hospitalized Parkinson's Disease Patients at Risk.

Authors:  Matthew Grissinger
Journal:  P T       Date:  2018-01

5.  Medication management in people with Parkinson's disease during surgical admissions.

Authors:  C P Derry; K J Shah; L Caie; C E Counsell
Journal:  Postgrad Med J       Date:  2010-06       Impact factor: 2.401

6.  Pharmacist- versus physician-obtained medication histories.

Authors:  Todd A Reeder; Alan Mutnick
Journal:  Am J Health Syst Pharm       Date:  2008-05-01       Impact factor: 2.637

7.  Missing dosages and neuroleptic usage may prolong length of stay in hospitalized Parkinson's disease patients.

Authors:  Daniel Martinez-Ramirez; Juan C Giugni; Christopher S Little; John P Chapman; Bilal Ahmed; Erin Monari; Aparna Wagle Shukla; Christopher W Hess; Michael S Okun
Journal:  PLoS One       Date:  2015-04-17       Impact factor: 3.240

  7 in total

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