Literature DB >> 3348695

An improved technique to facilitate transcervical thymectomy for myasthenia gravis.

J D Cooper1, A N Al-Jilaihawa, F G Pearson, J G Humphrey, H E Humphrey.   

Abstract

We have used the transcervical method of thymectomy in patients with myasthenia gravis and believe that complete thymectomy is accomplished with minimum morbidity. For the past eight years we have used an improved technique for the transcervical approach, employing a specially designed sternal retractor that permits improved visualization of the anterior mediastinum. We have reviewed 65 patients operated on between 1977 and 1986. Patients were assessed using a modified Osserman classification (0 = asymptomatic; 1 = ocular signs and symptoms; 2 = mild generalized weakness; 3 = moderate generalized weakness; 4 = severe generalized weakness, respiratory dysfunction, or both). The mean grade for all patients at the time of thymectomy was 2.7. At most recent follow-up, the mean clinical grade was 0.5. In addition, 85% of patients were free of generalized weakness, 95% had improved by at least one grade, and 86% had improved by two or more grades. Comparing these results with those reported following thymectomy through a sternotomy reveals that the transcervical approach gives equivalent results.

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Year:  1988        PMID: 3348695     DOI: 10.1016/s0003-4975(10)62457-5

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  35 in total

1.  Improved outcomes with surgery vs. medical therapy in non-thymomatous myesthenia gravis: a perspective on the results of a randomized trial.

Authors:  Olugbenga T Okusanya; Nick Hess; Neil Christie; James D Luketich; Inderpal S Sarkaria
Journal:  Ann Transl Med       Date:  2016-12

2.  Inclusion of the transcervical approach in video-assisted thoracoscopic extended thymectomy (VATET) for myasthenia gravis: a prospective trial.

Authors:  N Shigemura; H Shiono; M Inoue; M Minami; M Ohta; M Okumura; H Matsuda
Journal:  Surg Endosc       Date:  2006-06-22       Impact factor: 4.584

3.  Limited upper sternotomy in general thoracic surgery.

Authors:  Marco Alifano; Sergio N Forti Parri; Walid Abu Arab; Barbara Bonfanti; Nicola Lacava; Calogero Porrello; Maurizio Boaron
Journal:  Surg Today       Date:  2008-03-27       Impact factor: 2.549

4.  Video-assisted thoracoscopic surgery versus sternotomy in thymectomy for thymoma and myasthenia gravis.

Authors:  Adnan Raza; Edwin Woo
Journal:  Ann Cardiothorac Surg       Date:  2016-01

Review 5.  Minimally invasive versus open thymectomy: a systematic review of surgical techniques, patient demographics, and perioperative outcomes.

Authors:  Nicholas R Hess; Inderpal S Sarkaria; Arjun Pennathur; Ryan M Levy; Neil A Christie; James D Luketich
Journal:  Ann Cardiothorac Surg       Date:  2016-01

Review 6.  Thymectomy for myasthenia gravis.

Authors:  J D Urschel; R P Grewal
Journal:  Postgrad Med J       Date:  1998-03       Impact factor: 2.401

7.  Extended cervicomediastinal thymectomy in the integrated management of myasthenia gravis.

Authors:  G B Bulkley; K N Bass; G R Stephenson; M Diener-West; S George; P A Reilly; R R Baker; D B Drachman
Journal:  Ann Surg       Date:  1997-09       Impact factor: 12.969

Review 8.  Uniportal subxiphoid video-assisted thoracoscopic thymectomy.

Authors:  Takashi Suda
Journal:  J Vis Surg       Date:  2016-07-22

Review 9.  [Minimally invasive thymus surgery].

Authors:  J C Rückert; M Ismail; M Swierzy; C Braumann; H Badakhshi; P Rogalla; A Meisel; R I Rückert; J M Müller
Journal:  Chirurg       Date:  2008-01       Impact factor: 0.955

10.  Endoscopic robot-assisted extended thymectomy by subxiphoid approach with sternal lifting: feasibility in the pig.

Authors:  P F A Bakker; R P J Budde; P F Gründeman
Journal:  Surg Endosc       Date:  2004-04-27       Impact factor: 4.584

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