| Literature DB >> 33486675 |
Ruth Saez-Maleta1, Ana Merino-Merino2, Simon Gundin-Menendez1, Ricardo Salgado-Aranda2, Daniel AlKassam-Martinez1,3, Virginia Pascual-Tejerina2, Javier Martin-Gonzalez2, Javier Garcia-Fernandez2, Jose-Angel Perez-Rivera4,5.
Abstract
Genotyping of ST2 and galectin-3 in atrial fibrillation (AF) is not well analyzed. The aim of our study was to analyze the possible relationship between levels of sST2 and galectin-3 and three polymorphisms in patients with AF. We included 125 patients with persistent AF undergoing electric cardioversion. We analyzed sST2 and galectin-3 levels and three polymorphisms in peripheral blood samples. Rs2274273 was significantly related with levels of galectin-3. Rs1558648 was associated with levels of sST2 but rs13019803 were not. None of the polymorphisms were connected to the variation of biomarkers levels during the follow up. We found a relationship between rs2274273 and galectin-3 levels and rs1558648 and sST2 levels in patients with AF.Entities:
Keywords: Atrial fibrillation; Biomarkers; Galectin 3; Polymorphisms; sST2
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Year: 2021 PMID： 33486675 DOI： 10.1007/s11033-021-06150-1
Source DB: PubMed Journal: Mol Biol Rep ISSN： 0301-4851 Impact factor: 2.316