Literature DB >> 3348607

Enterohepatic circulation of NY-198, a new difluorinated quinolone, in rats.

A Saito1, O Nagata, Y Takahara, E Okezaki, T Yamada, Y Ito.   

Abstract

Enterohepatic circulation of NY-198 in rats was studied. NY-198 glucuronide in the bile was rapidly hydrolyzed to NY-198 by the intestinal contents. Hydrolyzed and parent NY-198 in the bile were reabsorbed from the intestine. The amount of NY-198 in enterohepatic circulation was 59.8% of that excreted in the bile.

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Year:  1988        PMID： 3348607      PMCID： PMC172121          DOI： 10.1128/AAC.32.1.156

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  4 in total

1.  In vitro and in vivo activity of NY-198, a new difluorinated quinolone.

Authors:  T Hirose; E Okezaki; H Kato; Y Ito; M Inoue; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1987-06       Impact factor: 5.191

2.  IUPAC Commission on the Nomenclature of Organic Chemistry (CON) and IUPAC-IUB Commission on Biochemical Nomenclature (CBN). The nomenclature of cyclitols. Tentative rules.

Authors: 
Journal:  Biochem J       Date:  1969-03       Impact factor: 3.857

3.  Excretion and re-excretion of a broad-spectrum penicillin in bile.

Authors:  G T STEWART; P M HARRISON
Journal:  Br J Pharmacol Chemother       Date:  1961-12

4.  Observations on the metabolic disposition of chloramphenicol (chloromycetin) in the rat.

Authors:  A J GLAZKO; W A DILL; L M WOLF
Journal:  J Pharmacol Exp Ther       Date:  1952-04       Impact factor: 4.030
  4 in total
  1 in total

1.  Pharmacokinetics of a novel quinolone, AT-4140, in animals.

Authors:  S Nakamura; N Kurobe; T Ohue; M Hashimoto; M Shimizu
Journal:  Antimicrob Agents Chemother       Date:  1990-01       Impact factor: 5.191
  1 in total

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