Literature DB >> 3348567

A stool collection device: the first step in occult blood testing.

D A Ahlquist1, S Schwartz, J Isaacson, M Ellefson.   

Abstract

Despite widespread fecal blood testing, the technique of gathering stool for sampling has remained uncontrolled. We sought to describe how patients have contended with this awkward step, to study artifact caused by toilet water, and to construct a collection device that prevents sampling problems. A survey of 250 patients showed that most (56%) had retrieved stools from the toilet basin, 17% used a pan or other household receptacle, 10% used newspaper or tissue paper, and 17% had been unable or unwilling. Sampling stool from the toilet basin introduces error because 4% to 75% of blood leaches from the fecal surface into surrounding water after only 4 to 12 minutes, and many toilet sanitizers cause false-positive guaiac reactions. We describe an inexpensive, disposable stool collector; outpatient compliance has been 97% using this device. To avoid biochemical artifact and facilitate stool sampling, we advocate that a collection device be incorporated into the occult blood testing process.

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Year:  1988        PMID: 3348567     DOI: 10.7326/0003-4819-108-4-609

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN: 0003-4819            Impact factor:   25.391


  6 in total

1.  Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation.

Authors:  S F Jørgensen; M Trøseid; M Kummen; J A Anmarkrud; A E Michelsen; L T Osnes; K Holm; M L Høivik; A Rashidi; C P Dahl; M Vesterhus; B Halvorsen; T E Mollnes; R K Berge; B Moum; K E A Lundin; B Fevang; T Ueland; T H Karlsen; P Aukrust; J R Hov
Journal:  Mucosal Immunol       Date:  2016-03-16       Impact factor: 7.313

2.  The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study.

Authors:  Johannes R Hov; Huanzi Zhong; Bingcai Qin; Jarl Andreas Anmarkrud; Kristian Holm; Andre Franke; Benedicte A Lie; Tom H Karlsen
Journal:  PLoS One       Date:  2015-07-24       Impact factor: 3.240

3.  Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency.

Authors:  S F Jørgensen; M E Macpherson; T Bjørnetrø; K Holm; M Kummen; A Rashidi; A E Michelsen; T Lekva; B Halvorsen; M Trøseid; T E Mollnes; R K Berge; A Yndestad; T Ueland; T H Karlsen; P Aukrust; J R Hov; B Fevang
Journal:  Sci Rep       Date:  2019-01-17       Impact factor: 4.379

4.  Altered Plasma Fatty Acids Associate with Gut Microbial Composition in Common Variable Immunodeficiency.

Authors:  Tonje Skarpengland; Magnhild E Macpherson; Johannes R Hov; Xiang Y Kong; Pavol Bohov; Bente Halvorsen; Børre Fevang; Rolf K Berge; Pål Aukrust; Silje F Jørgensen
Journal:  J Clin Immunol       Date:  2021-10-20       Impact factor: 8.317

5.  Rosuvastatin alters the genetic composition of the human gut microbiome.

Authors:  Martin Kummen; Ole Geir Solberg; Christopher Storm-Larsen; Kristian Holm; Asgrimur Ragnarsson; Marius Trøseid; Beate Vestad; Rita Skårdal; Arne Yndestad; Thor Ueland; Asbjørn Svardal; Rolf K Berge; Ingebjørg Seljeflot; Lars Gullestad; Tom H Karlsen; Lars Aaberge; Pål Aukrust; Johannes R Hov
Journal:  Sci Rep       Date:  2020-03-25       Impact factor: 4.379

6.  Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency.

Authors:  Magnhild E Macpherson; Johannes R Hov; Thor Ueland; Tuva B Dahl; Martin Kummen; Kari Otterdal; Kristian Holm; Rolf K Berge; Tom E Mollnes; Marius Trøseid; Bente Halvorsen; Pål Aukrust; Børre Fevang; Silje F Jørgensen
Journal:  Front Immunol       Date:  2020-09-16       Impact factor: 7.561

  6 in total

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