Literature DB >> 33485525

Where to Next for Optimizing Adherence in Large-Scale Trials of Continuous Positive Airway Pressure?

Amy M Sawyer1, Douglas M Wallace2, Luis F Buenaver3, Alexa J Watach4, Amy Blase5, Bruno Saconi6, Sanjay R Patel7, Samuel T Kuna8, Naresh M Punjabi9.   

Abstract

Large-scale randomized trials of positive airway pressure (PAP) efficacy have been largely negative but PAP adherence was notably suboptimal across the trials. To address this limitation, evidence-based PAP adherence protocols embedded within the larger trial protocol are recommended. The complexity of such protocols depends on adequacy of resources, including funding and inclusion of behavioral scientist experts on the scientific team, and trial-specific considerations (eg, target population) and methods. Recommendations for optimizing PAP adherence in large-scale trials are set forth that address rigor and reproducibility. Published by Elsevier Inc.

Entities:  

Keywords:  Behavioral economics; Continuous positive airway pressure; Controlled clinical trial; Health behavior; Health education; Obstructive sleep apnea; Patient compliance; Telemedicine

Mesh:

Year:  2020        PMID: 33485525     DOI: 10.1016/j.jsmc.2020.10.007

Source DB:  PubMed          Journal:  Sleep Med Clin        ISSN: 1556-407X


  3 in total

1.  Randomized clinical trials of cardiovascular disease in obstructive sleep apnea: understanding and overcoming bias.

Authors:  Allan I Pack; Ulysses J Magalang; Bhajan Singh; Samuel T Kuna; Brendan T Keenan; Greg Maislin
Journal:  Sleep       Date:  2021-02-12       Impact factor: 5.849

2.  To RCT or not to RCT? Depends on the question. A response to McEvoy et al.

Authors:  Allan I Pack; Ulysses J Magalang; Bhajan Singh; Samuel T Kuna; Brendan T Keenan; Greg Maislin
Journal:  Sleep       Date:  2021-04-09       Impact factor: 5.849

Review 3.  Personalized and Patient-Centered Strategies to Improve Positive Airway Pressure Adherence in Patients with Obstructive Sleep Apnea.

Authors:  Alexa J Watach; Dennis Hwang; Amy M Sawyer
Journal:  Patient Prefer Adherence       Date:  2021-07-12       Impact factor: 2.314

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.