Literature DB >> 33485396

Colorectal resection in endometriosis patients: correlation between histopathological findings and postoperative outcome.

Peter Tschann1, Nikola Vitlarov2, Martin Hufschmidt3, Daniel Lechner3, Paolo N C Girotti3, Felix Offner2, Burghard Abendstein4, Ingmar Königsrainer3.   

Abstract

INTRODUCTION: Endometriosis is associated with a high number of chronic pelvic pain and reduced quality of life. Colorectal resections in case of bowel involvement of endometriosis are associated with an unneglectable morbidity in young and healthy patients. There is no linear correlation established between the degree of symptoms and stage of endometriosis. The aim of this study was to correlate the histological findings to preoperative pain scores in colorectal resected patients with endometriosis.
METHODS: Twenty-five patients who underwent laparoscopic colorectal resection for endometriosis between 2014 and 2019 were included in this retrospective study. Pain level was assessed preoperatively and postoperatively via phone call in May 2020. Histopathology was correlated to preoperative symptoms and postoperative outcome.
RESULTS: Average follow-up time was 38.68 months (± 19.92). Preoperative VAS-score was 8.32 (± 1.70). We observed a significant reduction of pain level in all patients after surgery (p ≤ 0.005). Pain levels were equal regarding the presence of satellite spots and various degrees of infiltration depth. The resection margins were clear in all patients. Postoperative complications occurred in 6 cases (24%) and anastomotic leakage was observed in 3 patients (12%). Average VAS-score at time of follow-up was 1.70 (± 2.54).
CONCLUSION: Our data demonstrate that adequate colorectal resection leads to reduction of pain and an increase of quality of life irrespective of histopathological findings. An experienced team is necessary to improve intraoperative outcome and to reduce postoperative morbidity in case of complication.

Entities:  

Keywords:  Bowel involvement; Colorectal resection; Endometriosis; Histopathology; Pain level

Mesh:

Year:  2021        PMID: 33485396      PMCID: PMC7824935          DOI: 10.1186/s40001-021-00484-z

Source DB:  PubMed          Journal:  Eur J Med Res        ISSN: 0949-2321            Impact factor:   2.175


  30 in total

Review 1.  Clinical practice. Endometriosis.

Authors:  Linda C Giudice
Journal:  N Engl J Med       Date:  2010-06-24       Impact factor: 91.245

2.  Laparoscopy in the diagnosis and management of pelvic pain in adolescents.

Authors:  D P Goldstein; C deCholnoky; S J Emans; J M Leventhal
Journal:  J Reprod Med       Date:  1980-06       Impact factor: 0.142

Review 3.  [Diagnosis accuracy of endoscopy (laparoscopy, hysteroscopy, fertiloscopy, cystoscopy, colonoscopy) in case of endometriosis: CNGOF-HAS Endometriosis Guidelines].

Authors:  A Tardieu; F Sire; T Gauthier
Journal:  Gynecol Obstet Fertil Senol       Date:  2018-03-09

4.  Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries.

Authors:  Kelechi E Nnoaham; Lone Hummelshoj; Premila Webster; Thomas d'Hooghe; Fiorenzo de Cicco Nardone; Carlo de Cicco Nardone; Crispin Jenkinson; Stephen H Kennedy; Krina T Zondervan
Journal:  Fertil Steril       Date:  2011-06-30       Impact factor: 7.329

5.  Segmental bowel resection for colorectal endometriosis: is there a correlation between histological pattern and clinical outcomes?

Authors:  M Mabrouk; E Spagnolo; D Raimondo; A D'Errico; G Caprara; D Malvi; F Catena; G Ferrini; R Paradisi; R Seracchioli
Journal:  Hum Reprod       Date:  2012-03-12       Impact factor: 6.918

Review 6.  Diagnosis of endometriosis in the 21st century.

Authors:  L Kiesel; M Sourouni
Journal:  Climacteric       Date:  2019-03-25       Impact factor: 3.005

Review 7.  Does intra-operative flexible endoscopy reduce anastomotic complications following left-sided colonic resections? A systematic review and meta-analysis.

Authors:  M Aly; J W O'Brien; F Clark; S Kapur; A T Stearns; I Shaikh
Journal:  Colorectal Dis       Date:  2019-07-17       Impact factor: 3.788

8.  Laparoscopic colorectal resection for bowel endometriosis: feasibility, complications, and clinical outcome.

Authors:  Luca Minelli; Francesco Fanfani; Anna Fagotti; Giacomo Ruffo; Marcello Ceccaroni; Liliana Mereu; Stefano Landi; Paola Pomini; Giovanni Scambia
Journal:  Arch Surg       Date:  2009-03

Review 9.  Do we really know why colorectal anastomoses leak?

Authors:  Benjamin D Shogan; Erica M Carlisle; John C Alverdy; Konstantin Umanskiy
Journal:  J Gastrointest Surg       Date:  2013-05-21       Impact factor: 3.452

Review 10.  Endometriosis and infertility: a review of the pathogenesis and treatment of endometriosis-associated infertility.

Authors:  Matthew Latham Macer; Hugh S Taylor
Journal:  Obstet Gynecol Clin North Am       Date:  2012-12       Impact factor: 2.844

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.