Literature DB >> 33483822

Use of High-Dose Influenza and Live Attenuated Influenza Vaccines by US Primary Care Physicians.

Jessica R Cataldi1,2, Laura P Hurley3,4, Megan C Lindley5, Sean T O'Leary3,6, Carol Gorman3, Michaela Brtnikova3,6, Brenda L Beaty3, Lori A Crane3,7, David K Shay5, Allison Kempe3,6.   

Abstract

BACKGROUND: Several different types of influenza vaccine are licensed for use in adults in the USA including high-dose inactivated influenza vaccine (HD-IIV) and live attenuated influenza vaccine (LAIV). HD-IIV is licensed for use in adults ≥ 65 years, and recommendations for use of LAIV have changed several times in recent years.
OBJECTIVE: We sought to examine family physicians' (FPs) and general internal medicine physicians' (GIMs) perceptions, knowledge, and practices for use of HD-IIV and LAIV during the 2016-2017 and 2018-2019 influenza seasons.
DESIGN: E-mail and mail surveys conducted February-March 2017, January-February 2019. PARTICIPANTS: Nationally representative samples of FPs and GIMs. MAIN MEASURES: Surveys assessed HD-IIV practices (2017), knowledge and perceptions (2019), and LAIV knowledge and practices (2017, 2019). KEY
RESULTS: Response rates were 67% (620/930) in 2017 and 69% (642/926) in 2019. Many physicians believed HD-IIV is more effective than standard dose IIV in patients ≥ 65 years (76%) and reported their patients ≥ 65 years believe they need HD-IIV (67%). Most respondents incorrectly thought ACIP preferentially recommends HD-IIV for adults ≥ 65 years (88%); 65% "almost always/always" recommended HD-IIV for adults ≥ 65 years. Some physicians incorrectly thought ACIP preferentially recommends HD-IIV for adults < 65 years with cardiopulmonary disease (38%) or immunosuppression (48%); some respondents recommended HD-IIV for these groups (25% and 28% respectively). In 2017, 88% of respondents knew that ACIP recommended against using LAIV during the 2016-2017 influenza season, and 4% recommended LAIV to patients. In 2019, 63% knew that ACIP recommended that LAIV could be used during the 2018-2019 influenza season, and 8% recommended LAIV.
CONCLUSIONS: Many physicians incorrectly thought ACIP had preferential recommendations for HD-IIV. Physicians should be encouraged to use any available age-appropriate influenza vaccine to optimize influenza vaccination particularly among older adults and patients with chronic conditions who are more vulnerable to severe influenza disease.
© 2021. Society of General Internal Medicine.

Entities:  

Keywords:  immunization; influenza; influenza vaccine; vaccination

Mesh:

Substances:

Year:  2021        PMID: 33483822      PMCID: PMC8298749          DOI: 10.1007/s11606-020-06397-7

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   6.473


  37 in total

1.  Direct-to-Consumer Pharmaceutical Advertising: Therapeutic or Toxic?

Authors:  C Lee Ventola
Journal:  P T       Date:  2011-10

2.  Sentinel physician networks as a technique for rapid immunization policy surveys.

Authors:  Lori A Crane; Matthew F Daley; Jennifer Barrow; Christine Babbel; Shannon Stokley; L Miriam Dickinson; Brenda L Beaty; John F Steiner; Allison Kempe
Journal:  Eval Health Prof       Date:  2008-01-08       Impact factor: 2.651

3.  Comparative effectiveness of high-dose versus standard-dose influenza vaccination on numbers of US nursing home residents admitted to hospital: a cluster-randomised trial.

Authors:  Stefan Gravenstein; H Edward Davidson; Monica Taljaard; Jessica Ogarek; Pedro Gozalo; Lisa Han; Vincent Mor
Journal:  Lancet Respir Med       Date:  2017-07-20       Impact factor: 30.700

4.  Influenza Activity - United States, 2015-16 Season and Composition of the 2016-17 Influenza Vaccine.

Authors:  Stacy L Davlin; Lenee Blanton; Krista Kniss; Desiree Mustaquim; Sophie Smith; Natalie Kramer; Jessica Cohen; Charisse Nitura Cummings; Shikha Garg; Brendan Flannery; Alicia M Fry; Lisa A Grohskopf; Joseph Bresee; Teresa Wallis; Wendy Sessions; Rebecca Garten; Xiyan Xu; Anwar Isa Abd Elal; Larisa Gubareva; John Barnes; David E Wentworth; Erin Burns; Jacqueline Katz; Daniel Jernigan; Lynnette Brammer
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2016-06-10       Impact factor: 17.586

5.  Cost-Effectiveness and Public Health Effect of Influenza Vaccine Strategies for U.S. Elderly Adults.

Authors:  Jonathan M Raviotta; Kenneth J Smith; Jay DePasse; Shawn T Brown; Eunha Shim; Mary Patricia Nowalk; Richard K Zimmerman
Journal:  J Am Geriatr Soc       Date:  2016-10-06       Impact factor: 5.562

Review 6.  Fluzone® High-Dose Influenza Vaccine.

Authors:  Corwin A Robertson; Carlos A DiazGranados; Michael D Decker; Ayman Chit; Monica Mercer; David P Greenberg
Journal:  Expert Rev Vaccines       Date:  2016-11-14       Impact factor: 5.217

7.  Comparison of the efficacy and safety of live attenuated cold-adapted influenza vaccine, trivalent, with trivalent inactivated influenza virus vaccine in children and adolescents with asthma.

Authors:  Douglas M Fleming; Pietro Crovari; Ulrich Wahn; Timo Klemola; Yechiel Schlesinger; Alexangros Langussis; Knut Øymar; Maria Luz Garcia; Alain Krygier; Herculano Costa; Ulrich Heininger; Jean-Louis Pregaldien; Sheau-Mei Cheng; Jonathan Skinner; Ahmad Razmpour; Melanie Saville; William C Gruber; Bruce Forrest
Journal:  Pediatr Infect Dis J       Date:  2006-10       Impact factor: 2.129

8.  Superior relative efficacy of live attenuated influenza vaccine compared with inactivated influenza vaccine in young children with recurrent respiratory tract infections.

Authors:  Shai Ashkenazi; Andre Vertruyen; Javier Arístegui; Susanna Esposito; David Douglas McKeith; Timo Klemola; Jiri Biolek; Joachim Kühr; Tadeusz Bujnowski; Daniel Desgrandchamps; Sheau-Mei Cheng; Jonathan Skinner; William C Gruber; Bruce D Forrest
Journal:  Pediatr Infect Dis J       Date:  2006-10       Impact factor: 2.129

Review 9.  Efficacy and effectiveness of high-dose versus standard-dose influenza vaccination for older adults: a systematic review and meta-analysis.

Authors:  Jason K H Lee; Gary K L Lam; Thomas Shin; Jiyeon Kim; Anish Krishnan; David P Greenberg; Ayman Chit
Journal:  Expert Rev Vaccines       Date:  2018-05-16       Impact factor: 5.217

10.  Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices-United States, 2018-19 Influenza Season.

Authors:  Lisa A Grohskopf; Leslie Z Sokolow; Karen R Broder; Emmanuel B Walter; Alicia M Fry; Daniel B Jernigan
Journal:  MMWR Recomm Rep       Date:  2018-08-24
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