| Literature DB >> 33483364 |
Nikkola Carmichael1,2, Jose M Martinez Manzano3, Luisa D Quesada-Arias3, Sergio de Frías Poli3, Maura Alvarez Baumgartner3, Maria A Planchart Ferretto3, Lisa DiGianni4,5, Shannon Gampala-Sagar4,5, Dominick A Leone5, Swati Gulati3, Souheil Y El-Chemaly3,6, Hilary J Goldberg3,6, Rachel Putman3,6, Hiroto Hatabu6,7, Ivan O Rosas8, Gary M Hunninghake3,6,7, Benjamin A Raby4,2,6.
Abstract
Screening for pulmonary fibrosis may help to identify early stages of the disease. We assessed the psychological impact of screening undiagnosed first-degree relatives of patients with pulmonary fibrosis by administering two validated measures after participants received their results: the Decisional Regret Scale and the Feelings About genomiC Testing Results Questionnaire. More than 90% of relatives reported either no or mild decisional regret. Increased measures of decisional regret and negative feelings were present in those found to have a low diffusion capacity of carbon monoxide or interstitial lung abnormalities. Results of telomere length and genetic testing did not significantly impact regret. © Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.Entities:
Keywords: idiopathic pulmonary fibrosis
Mesh：
Year: 2021 PMID： 33483364 PMCID： PMC8238310 DOI： 10.1136/thoraxjnl-2020-216244
Source DB: PubMed Journal: Thorax ISSN： 0040-6376 Impact factor: 9.102