Literature DB >> 33482850

Analgesic effect of single-shot ropivacaine at different layers of the surgical site in primary total hip arthroplasty: a randomised, controlled, observer-blinded study.

Qiang Xiao1,2, Bing Xu1, Haoyang Wang2, Zhenyu Luo2, Mingcheng Yuan2, Zongke Zhou3, Fuxing Pei2.   

Abstract

OBJECTIVES: The aim of this study was to evaluate the efficacy of local infiltration anaesthesia (LIA) during primary total hip arthroplasty (THA) via a posterolateral approach under general anaesthesia and to compare the efficacy of LIA in all layers with LIA in the deep and superficial fascia. PATIENTS AND METHODS: One hundred twenty patients were randomised into three groups: LIA in the deep and superficial fascia (group A), LIA in all layers (group B) and the control (group C). The primary outcomes were the visual analogue scale (VAS) pain scores at rest and on movement within 72 h (h) postoperatively. The secondary outcomes included opioid consumption, patient satisfaction, range of motion (ROM), straight leg raise completion rate, length of hospital stay, opioid-related side effects and wound complications. We followed the patients until 6 months after discharge.
RESULTS: At 2 and 6 h, groups A and B had lower resting VAS scores than group C (p < 0.01); at 12 h, group B had a lower resting VAS score than group C (p < 0.05). At 6 and 12 h, the movement VAS scores in groups A and B were lower than those in group C (p < 0.01). Groups A and B had similar VAS scores during the observation period. Groups A and B had higher levels of patient satisfaction than group C (p = 0.03 and p = 0.018, respectively). Opioid consumption was similar in the three groups. There were no significant differences in the other secondary outcomes amongst the three groups. No difference was found in hip rehabilitation or chronic pain during the follow-up period.
CONCLUSION: Single-shot LIA with ropivacaine alone reduces the pain score during the first 12 postoperative hours and improves patients' satisfaction with THA. LIA in the deep and superficial fascia and LIA in all layers have similar analgesic effects. LIA in the deep and superficial fascia may be an alternative method to LIA in all layers.

Entities:  

Keywords:  Local infiltration anaesthesia; Postoperative pain; Total hip arthroplasty

Mesh:

Substances:

Year:  2021        PMID: 33482850      PMCID: PMC7821717          DOI: 10.1186/s13018-020-02182-8

Source DB:  PubMed          Journal:  J Orthop Surg Res        ISSN: 1749-799X            Impact factor:   2.359


  25 in total

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Authors:  Masahiko Takahashi; Takeshi Ohara; Hiroyuki Yamanaka; Akira Shimada; Toshimichi Nakaho; Yamamuro Makoto
Journal:  Palliat Med       Date:  2003-12       Impact factor: 4.762

Review 2.  Multimodal pain management after total joint arthroplasty.

Authors:  Javad Parvizi; Adam G Miller; Kishor Gandhi
Journal:  J Bone Joint Surg Am       Date:  2011-06-01       Impact factor: 5.284

3.  Relative potency of controlled-release oxycodone and controlled-release morphine in a postoperative pain model.

Authors:  G B Curtis; G H Johnson; P Clark; R Taylor; J Brown; R O'Callaghan; M Shi; P G Lacouture
Journal:  Eur J Clin Pharmacol       Date:  1999-08       Impact factor: 2.953

Review 4.  Neuraxial vs general anaesthesia for total hip and total knee arthroplasty: a systematic review of comparative-effectiveness research.

Authors:  R L Johnson; S L Kopp; C M Burkle; C M Duncan; A K Jacob; P J Erwin; M H Murad; C B Mantilla
Journal:  Br J Anaesth       Date:  2016-02       Impact factor: 9.166

5.  Can a periarticular levobupivacaine injection reduce postoperative opiate consumption during primary hip arthroplasty?

Authors:  Terence P Murphy; Damien P Byrne; Paul Curtin; Joseph F Baker; Kevin J Mulhall
Journal:  Clin Orthop Relat Res       Date:  2011-09-30       Impact factor: 4.176

6.  Local infiltration analgesia followed by continuous infusion of local anesthetic solution for total hip arthroplasty: a prospective, randomized, double-blind, placebo-controlled study.

Authors:  Olga Solovyova; Courtland G Lewis; Jonathan H Abrams; John Grady-Benson; Michael E Joyce; Steven F Schutzer; Sivasenthil Arumugam; Stephanie Caminiti; Sanjay K Sinha
Journal:  J Bone Joint Surg Am       Date:  2013-11-06       Impact factor: 5.284

7.  Pharmacokinetics and efficacy of ropivacaine continuous wound instillation after joint replacement surgery.

Authors:  M Bianconi; L Ferraro; G C Traina; G Zanoli; T Antonelli; A Guberti; R Ricci; L Massari
Journal:  Br J Anaesth       Date:  2003-12       Impact factor: 9.166

8.  Post-operative analgesia following femoral-neck surgery--a comparison between 3 in 1 femoral nerve block and lateral cutaneous nerve block.

Authors:  N R Coad
Journal:  Eur J Anaesthesiol       Date:  1991-07       Impact factor: 4.330

9.  High-volume infiltration analgesia in bilateral hip arthroplasty. A randomized, double-blind placebo-controlled trial.

Authors:  Lasse Ø Andersen; Kristian S Otte; Henrik Husted; Lissi Gaarn-Larsen; Billy Kristensen; Henrik Kehlet
Journal:  Acta Orthop       Date:  2011-07-13       Impact factor: 3.717

Review 10.  Safety of liposome extended-release bupivacaine for postoperative pain control.

Authors:  Juan Portillo; Nawal Kamar; Somayah Melibary; Eduardo Quevedo; Sergio Bergese
Journal:  Front Pharmacol       Date:  2014-04-30       Impact factor: 5.810

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  1 in total

1.  Effect of Dexmedetomidine Combined with Ropivacaine on Cognitive Dysfunction and Inflammatory Response in Patients Undergoing Craniocerebral Surgery.

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Journal:  Biomed Res Int       Date:  2021-11-30       Impact factor: 3.411

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