Literature DB >> 33482457

Women with OSA have higher chances of having metabolic syndrome than men: effect of gender on syndrome Z in cross sectional study.

Poonam Chaudhary1, Abhishek Goyal2, S K Goel1, Ashok Kumar1, Swanzel Chaudhary3, Shashwat Kirti Keshri3, Rashmi Phadke Subhedar4.   

Abstract

STUDY
OBJECTIVES: This study was done to find out prevalence of Metabolic syndrome (MS) in patients with Obstructive Sleep Apnea (OSA) and whether there is any difference in prevalence of syndrome Z in male and female.
METHODOLOGY: All consecutive diagnosed patients with OSA between June 2015 and Oct 2019 were screened for metabolic syndrome and factors associated with metabolic syndrome in OSA were analyzed.
RESULTS: During study period, 502 patients (357 males; 145 females) were diagnosed with OSA. Mean age was 51.88 ± 12.18 years (females and males:55.91 ± 9.74 and 50.24 ± 12.70 years, respectively). Mean BMI was 31.60 ± 11.09 kg/m2 (female: 35.29 ± 7.19 and male: 30.1 ± 12.0 kg/m2) (p < 0.001). Mean AHI was 62.67 ± 35.22. Mild, moderate and severe category of OSA constituted 7.3%, 15.3% and 77.4% respectively. MS was found in 72.7% (365 out of 502) individuals with OSA. MS was found in 75.8%, 68.4 and 48.7% in severe, moderate and mild OSA patients respectively (p < 0.001). Females OSA patients had significantly high percentage (88.27%) of metabolic syndrome compared to males OSA patients (66.38%) {p < 0.001}. Female patients with SZ had higher metabolic score (p = 0.019) and were older (p < 0.001).
CONCLUSION: Metabolic syndrome is highly prevalent in OSA population (72.7%) and is much more common in female OSA patients (88%) than males OSA (68%). All OSA patients should be screened for MS so that early intervention can be done in these patients so as to prevent cardiovascular complications.
Copyright © 2021 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Continuous positive airway pressure; Metabolic syndrome; Obstructive sleep apnoea

Year:  2021        PMID: 33482457     DOI: 10.1016/j.sleep.2020.12.042

Source DB:  PubMed          Journal:  Sleep Med        ISSN: 1389-9457            Impact factor:   3.492


  6 in total

1.  Assessment of Obstructive Sleep Apnea in Association with Severity of COVID-19: A Prospective Observational Study.

Authors:  Avishek Kar; Khushboo Saxena; Abhishek Goyal; Abhijit Pakhare; Alkesh Khurana; Saurabh Saigal; Parneet Kaur Bhagtana; Sridevi S K R Chinta; Yogesh Niwariya
Journal:  Sleep Vigil       Date:  2021-05-06

2.  Obstructive sleep apnea is highly prevalent in COVID19 related moderate to severe ARDS survivors: findings of level I polysomnography in a tertiary care hospital.

Authors:  Abhishek Goyal; Khushboo Saxena; Avishek Kar; Alkesh Khurana; Parneet Kaur Bhagtana; Chinta Siva Koti Rupa Sridevi; Abhijit Pakhare
Journal:  Sleep Med       Date:  2021-06-19       Impact factor: 4.842

3.  Predictive factors for CPAP failure in obstructive sleep apnea patients.

Authors:  Abhishek Goyal; Ankur Joshi; Arun Mitra; Alkesh Khurana; Poonam Chaudhary
Journal:  Lung India       Date:  2021 Nov-Dec

4.  Association of Metabolic Syndrome With Long-Term Cardiovascular Risks and All-Cause Mortality in Elderly Patients With Obstructive Sleep Apnea.

Authors:  Lin Liu; Xiaofeng Su; Zhe Zhao; Jiming Han; Jianhua Li; Weihao Xu; Zijun He; Yinghui Gao; Kaibing Chen; Libo Zhao; Yan Gao; Huanhuan Wang; JingJing Guo; Junling Lin; Tianzhi Li; Xiangqun Fang
Journal:  Front Cardiovasc Med       Date:  2022-02-07

5.  Metabolic syndrome in non-obese patients with OSA: learning points of a cross-sectional study from a tertiary care hospital in Central India.

Authors:  Poonam Chaudhary; Abhishek Goyal; Abhijit Pakhare; S K Goel; Ashok Kumar; Mallu Abhinav Reddy; Vangala Anoohya
Journal:  Sleep Breath       Date:  2021-07-20       Impact factor: 2.816

Review 6.  Gender Issues in Obstructive Sleep Apnea.

Authors:  Jacqueline H Geer; Janet Hilbert
Journal:  Yale J Biol Med       Date:  2021-09-30
  6 in total

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