David B Agus1, Elizabeth M Jaffee2, Chi Van Dang3. 1. Lawrence J Ellison Institute for Transformative Medicine, University of Southern California, Los Angeles, CA 90064, USA. Electronic address: agus@usc.edu. 2. Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD, USA. 3. Ludwig Institute for Cancer Research, New York, NY, USA.