Innocenzo Rainero1, Mathew J Summers2, Michaela Monter3, Marco Bazzani4, Eleftheria Giannouli5, Georg Aumayr6, Dalila Burin7, Paolo Provero8,9, Alessandro E Vercelli10. 1. Department of Neuroscience, University of Torino, Torino, Italy. 2. Discipline of Psychology, School of Health and Behavioural Sciences, University of the Sunshine Coast, Queensland, Australia. 3. Gestio Socio Sanitaria al Mediterrani (GESMED), Valencia, Spain. 4. LINKS Foundation, Torino, Italy. 5. German Sport University, Cologne, Germany. 6. Department of Research and Innovation, Johanniter Osterreich Ausbildung und Forschung gem, GmbH, Vienna, Austria. 7. Smart Aging Research Center (SARC), Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai, Japan. 8. Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy. 9. Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy. 10. Department of Neuroscience, Neuroscience Institute Cavalieri Ottolenghi, University of Torino, Torino, Italy.
Abstract
INTRODUCTION: Prevention of frailty is paramount in older adults. We evaluated the efficacy of a tailored multidomain intervention, monitored with the My Active and Healthy Aging platform, in reducing conversion from a prefrail status to overt frailty and preventing decline in quality of life. METHODS: We performed a multicentre, multicultural, randomised control study. The effects of multidomain interventions on frailty parameters, quality of life, physical, cognitive, psychosocial function, nutrition and sleep were evaluated in a group of 101 prefrail older subjects and compared with 100 prefrail controls, receiving general health advice. RESULTS: At the 12-month assessment, controls showed a decline in quality of life that was absent in the active group. In addition, active participants showed an increase in mood and nutrition function. No effect on remaining parameter was observed. DISCUSSION: Our study supports the use of personalised multidomain intervention, monitored with an information and communication technology platform, in preventing quality of life decline in older adults.
RCT Entities:
INTRODUCTION: Prevention of frailty is paramount in older adults. We evaluated the efficacy of a tailored multidomain intervention, monitored with the My Active and Healthy Aging platform, in reducing conversion from a prefrail status to overt frailty and preventing decline in quality of life. METHODS: We performed a multicentre, multicultural, randomised control study. The effects of multidomain interventions on frailty parameters, quality of life, physical, cognitive, psychosocial function, nutrition and sleep were evaluated in a group of 101 prefrail older subjects and compared with 100 prefrail controls, receiving general health advice. RESULTS: At the 12-month assessment, controls showed a decline in quality of life that was absent in the active group. In addition, active participants showed an increase in mood and nutrition function. No effect on remaining parameter was observed. DISCUSSION: Our study supports the use of personalised multidomain intervention, monitored with an information and communication technology platform, in preventing quality of life decline in older adults.
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