Literature DB >> 33479909

Regulatory B Cells in Experimental Mouse Models of Arthritis.

Diana E Matei1, Claudia Mauri2, Elizabeth C Rosser2.   

Abstract

Regulatory B cells (Breg) have been shown to have a role in the suppression of a wide variety of immune responses, yet they are deficient or defective in autoimmune diseases such as rheumatoid arthritis. For the study of autoimmune inflammation, experimental models of arthritis have acted as a valuable tool in understanding the development of Bregs and their role in maintaining immune homeostasis. In this chapter, we will focus on the study of transitional-2 marginal zone precursor (T2-MZP) Bregs in the context of two experimental arthritis models: antigen-induced arthritis (AIA) and collagen-induced arthritis (CIA). We will specifically focus on how to induce arthritis, as well as on methods for the isolation and functional study of Bregs both in vitro and in vivo.

Entities:  

Keywords:  Arthritis; Autoimmunity; IL-10; Inflammation; Regulatory B cells; T2-MZP B cells

Mesh：

Substances：

Year:  2021        PMID： 33479909     DOI： 10.1007/978-1-0716-1237-8_20

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  12 in total

1.  Novel suppressive function of transitional 2 B cells in experimental arthritis.

Authors:  Jamie G Evans; Karina A Chavez-Rueda; Ayad Eddaoudi; Almut Meyer-Bahlburg; David J Rawlings; Michael R Ehrenstein; Claudia Mauri
Journal:  J Immunol       Date:  2007-06-15       Impact factor: 5.422

2.  IL-12p35 subunit contributes to autoimmunity by limiting IL-27-driven regulatory responses.

Authors:  Rita Vasconcellos; Natalie A Carter; Elizabeth C Rosser; Claudia Mauri
Journal:  J Immunol       Date:  2011-08-15       Impact factor: 5.422

3.  Mice lacking endogenous IL-10-producing regulatory B cells develop exacerbated disease and present with an increased frequency of Th1/Th17 but a decrease in regulatory T cells.

Authors:  Natalie A Carter; Rita Vasconcellos; Elizabeth C Rosser; Calogero Tulone; Alba Muñoz-Suano; Masahito Kamanaka; Michael R Ehrenstein; Richard A Flavell; Claudia Mauri
Journal:  J Immunol       Date:  2011-04-04       Impact factor: 5.422

4.  In Vivo Models of Rheumatoid Arthritis.

Authors:  Bettina Grötsch; Aline Bozec; Georg Schett
Journal:  Methods Mol Biol       Date:  2019

5.  Antigen-induced arthritis in mice. I. Induction of arthritis in various strains of mice.

Authors:  D Brackertz; G F Mitchell; I R Mackay
Journal:  Arthritis Rheum       Date:  1977-04

6.  Collagen-induced arthritis.

Authors:  David D Brand; Kary A Latham; Edward F Rosloniec
Journal:  Nat Protoc       Date:  2007       Impact factor: 13.491

7.  Regulatory B cells are induced by gut microbiota-driven interleukin-1β and interleukin-6 production.

Authors:  Elizabeth C Rosser; Kristine Oleinika; Silvia Tonon; Ronan Doyle; Anneleen Bosma; Natalie A Carter; Kathryn A Harris; Simon A Jones; Nigel Klein; Claudia Mauri
Journal:  Nat Med       Date:  2014-10-19       Impact factor: 53.440

8.  Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis.

Authors:  Natalie A Carter; Elizabeth C Rosser; Claudia Mauri
Journal:  Arthritis Res Ther       Date:  2012-02-08       Impact factor: 5.156

9.  Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells.

Authors:  Christopher J M Piper; Elizabeth C Rosser; Kristine Oleinika; Kiran Nistala; Thomas Krausgruber; André F Rendeiro; Aggelos Banos; Ignat Drozdov; Matteo Villa; Scott Thomson; Georgina Xanthou; Christoph Bock; Brigitta Stockinger; Claudia Mauri
Journal:  Cell Rep       Date:  2019-11-12       Impact factor: 9.423

10.  Prevention of arthritis by interleukin 10-producing B cells.

Authors:  Claudia Mauri; David Gray; Naseem Mushtaq; Marco Londei
Journal:  J Exp Med       Date:  2003-02-17       Impact factor: 14.307
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