Literature DB >> 33479607

Meridianin D analogues possess antibiofilm activity against Mycobacterium smegmatis.

Sara M Brackett1, Karlie E Cox1, Samantha L Barlock1, William M Huggins2, David F Ackart3, Randall J Bassaraba3, Roberta J Melander1, Christian Melander1.   

Abstract

The formation of bacterial biofilms significantly decreases the efficacy of antibiotic treatments. Herein, we've investigated the antibiofilm properties of the natural product meridianin D and a library of analogues against Mycobacterium smegmatis. As a result, we discovered several analogues that both inhibit and disperse M. smegmatis biofilms. This journal is © The Royal Society of Chemistry 2020.

Entities:  

Year:  2019        PMID： 33479607      PMCID： PMC7523022          DOI： 10.1039/c9md00466a

Source DB:  PubMed          Journal:  RSC Med Chem        ISSN： 2632-8682


  17 in total

Review 1.  Riddle of biofilm resistance.

Authors:  K Lewis
Journal:  Antimicrob Agents Chemother       Date:  2001-04       Impact factor: 5.191

2.  Meridianins, a new family of protein kinase inhibitors isolated from the ascidian Aplidium meridianum.

Authors:  Marie Gompel; Maryse Leost; Elisa Bal De Kier Joffe; Lydia Puricelli; Laura Hernandez Franco; Jorge Palermo; Laurent Meijer
Journal:  Bioorg Med Chem Lett       Date:  2004-04-05       Impact factor: 2.823

Review 3.  The crisis in antibiotic resistance.

Authors:  H C Neu
Journal:  Science       Date:  1992-08-21       Impact factor: 47.728

Review 4.  Treatment of Tuberculosis.

Authors:  C Robert Horsburgh; Clifton E Barry; Christoph Lange
Journal:  N Engl J Med       Date:  2015-11-26       Impact factor: 91.245

5.  Microbiology. Desperately seeking new antibiotics.

Authors:  David J Payne
Journal:  Science       Date:  2008-09-19       Impact factor: 47.728

6.  Meridianin D Analogues Display Antibiofilm Activity against MRSA and Increase Colistin Efficacy in Gram-Negative Bacteria.

Authors:  William M Huggins; William T Barker; James T Baker; Nicholas A Hahn; Roberta J Melander; Christian Melander
Journal:  ACS Med Chem Lett       Date:  2018-05-25       Impact factor: 4.345

7.  Identification of Anti-Mycobacterial Biofilm Agents Based on the 2-Aminoimidazole Scaffold.

Authors:  T Vu Nguyen; Bradley M Minrovic; Roberta J Melander; Christian Melander
Journal:  ChemMedChem       Date:  2019-03-21       Impact factor: 3.466

8.  Synthesis and antitumor activity of indolylpyrimidines: marine natural product meridianin D analogues.

Authors:  Mohamed A A Radwan; Mahmoud El-Sherbiny
Journal:  Bioorg Med Chem       Date:  2006-11-16       Impact factor: 3.641

9.  Reversal of Mycobacterium tuberculosis phenotypic drug resistance by 2-aminoimidazole-based small molecules.

Authors:  David F Ackart; Erick A Lindsey; Brendan K Podell; Roberta J Melander; Randall J Basaraba; Christian Melander
Journal:  Pathog Dis       Date:  2014-02-24       Impact factor: 3.166

10.  An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.

Authors:  Aaron T Garrison; Yasmeen Abouelhassan; Dimitris Kallifidas; Hao Tan; Young S Kim; Shouguang Jin; Hendrik Luesch; Robert W Huigens
Journal:  J Med Chem       Date:  2018-04-19       Impact factor: 7.446
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  4 in total

1.  Second-Generation Meridianin Analogues Inhibit the Formation of Mycobacterium smegmatis Biofilms and Sensitize Polymyxin-Resistant Gram-Negative Bacteria to Colistin.

Authors:  Michael J Zeiler; Roberta J Melander; Christian Melander
Journal:  ChemMedChem       Date:  2020-08-03       Impact factor: 3.466

2.  2-Aminoimidazole Reduces Fouling and Improves Membrane Performance.

Authors:  Ariel J Atkinson; Mikayla D Armstrong; John T Eskew; Orlando Coronell
Journal:  J Memb Sci       Date:  2021-03-19       Impact factor: 10.530

3.  2-Aminoimidazoles Inhibit Mycobacterium abscessus Biofilms in a Zinc-Dependent Manner.

Authors:  Juan M Belardinelli; Wei Li; Kevin H Martin; Michael J Zeiler; Elena Lian; Charlotte Avanzi; Crystal J Wiersma; Tuan Vu Nguyen; Bhanupriya Angala; Vinicius C N de Moura; Victoria Jones; Bradley R Borlee; Christian Melander; Mary Jackson
Journal:  Int J Mol Sci       Date:  2022-03-09       Impact factor: 5.923

Review 4.  Strategies and Approaches for Discovery of Small Molecule Disruptors of Biofilm Physiology.

Authors:  Michael A Trebino; Rahul D Shingare; John B MacMillan; Fitnat H Yildiz
Journal:  Molecules       Date:  2021-07-29       Impact factor: 4.411
  4 in total

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