Manuel Sánchez-Luna1, Belén Fernández Colomer2, Concepción de Alba Romero3, Ana Alarcón Allen4, Ana Baña Souto5, Fátima Camba Longueira6, María Cernada Badía7, Zenaida Galve Pradell8, María González López9, M Cruz López Herrera10, Carmen Ribes Bautista6, Laura Sánchez García11, Elena Zamora Flores12. 1. Department of Neonatology, Hospital General Universitario Gregorio Marañón and Complutense University of Madrid, Madrid, Spain; msluna@salud.madrid.org. 2. Neonatology Service, Department of Pediatrics, Hospital Central Universitario de Asturias, Oviedo, Spain. 3. Neonatology Service, Hospital Universitario 12 de Octubre, Madrid, Spain. 4. Department of Neonatology, Hospital Sant Joan de Déu Barcelona, Barcelona, Spain. 5. Neonatology Service, Department of Pediatrics, Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain. 6. Department of Neonatology, Hospital Universitari Vall d'Hebron and Universitat Autònoma de Barcelona, Barcelona, Spain. 7. Division of Neonatology, Hospital Universitari i Politècnic La Fe, Valencia, Spain. 8. Department of Neonatology, Hospital Universitario Miguel Servet, Zaragoza, Spain. 9. Department of Neonatology, Hospital Regional Universitario de Málaga, Málaga, Spain. 10. Neonatology Service, Hospital Universitario de Cruces, Barakaldo, Spain; and. 11. Department of Neonatology, Hospital Universitario La Paz, Madrid, Spain. 12. Department of Neonatology, Hospital General Universitario Gregorio Marañón and Complutense University of Madrid, Madrid, Spain.
Abstract
OBJECTIVES: To describe neonatal and maternal characteristics of the largest prospective cohort of newborns from mothers with coronavirus disease 2019 (COVID-19), the data of which were prospectively collected from the nationwide registry of the Spanish Society of Neonatology. METHODS: Between March 8, 2020, and May 26, 2020, the data of 503 neonates born to 497 mothers diagnosed with COVID-19 during pregnancy or at the time of delivery were collected by 79 hospitals throughout Spain. RESULTS: Maternal symptoms were similar to that of the general population, with 5% of severe forms. In 45.8% of asymptomatic women at the time of delivery, severe acute respiratory syndrome coronavirus 2 infection was detected because of recommendations established in Spain to perform COVID-19 screening in all women admitted to the hospital for labor. The rate of preterm deliveries was 15.7% and of cesarean deliveries, 33%. The most common diagnostic test was detection of viral RNA by polymerase chain reaction of nasopharyngeal swabs at a median age of 3 hours after delivery (1-12 hours). Almost one-half of neonates were left skin-to-skin after delivery, and delayed clamping of umbilical cords was performed in 43% of neonates. Also, 62.3% of asymptomatic neonates were managed with rooming-in. Maternal milk was received by 76.5% of neonates, 204 of them as exclusive breastfeeding. CONCLUSIONS: The current study indicates that there is no need for separation of mothers from neonates, allowing delayed cord clamping and skin-to-skin contact along with maintenance of breastfeeding in a high percentage of newborns from mothers with COVID-19.
OBJECTIVES: To describe neonatal and maternal characteristics of the largest prospective cohort of newborns from mothers with coronavirus disease 2019 (COVID-19), the data of which were prospectively collected from the nationwide registry of the Spanish Society of Neonatology. METHODS: Between March 8, 2020, and May 26, 2020, the data of 503 neonates born to 497 mothers diagnosed with COVID-19 during pregnancy or at the time of delivery were collected by 79 hospitals throughout Spain. RESULTS: Maternal symptoms were similar to that of the general population, with 5% of severe forms. In 45.8% of asymptomatic women at the time of delivery, severe acute respiratory syndrome coronavirus 2 infection was detected because of recommendations established in Spain to perform COVID-19 screening in all women admitted to the hospital for labor. The rate of preterm deliveries was 15.7% and of cesarean deliveries, 33%. The most common diagnostic test was detection of viral RNA by polymerase chain reaction of nasopharyngeal swabs at a median age of 3 hours after delivery (1-12 hours). Almost one-half of neonates were left skin-to-skin after delivery, and delayed clamping of umbilical cords was performed in 43% of neonates. Also, 62.3% of asymptomatic neonates were managed with rooming-in. Maternal milk was received by 76.5% of neonates, 204 of them as exclusive breastfeeding. CONCLUSIONS: The current study indicates that there is no need for separation of mothers from neonates, allowing delayed cord clamping and skin-to-skin contact along with maintenance of breastfeeding in a high percentage of newborns from mothers with COVID-19.
Authors: Sara Vigil-Vázquez; Itziar Carrasco-García; Alicia Hernanz-Lobo; Ángela Manzanares; Alba Pérez-Pérez; Javier Toledano-Revenga; Mar Muñoz-Chapuli; Lara Mesones-Guerra; Andrea Martínez-Lozano; Beatriz Pérez-Seoane; Elena Márquez-Isidro; Olga Sanz-Asín; Gloria Caro-Chinchilla; Marta Sardá-Sánchez; Álvaro Solaz-García; Juan López-Carnero; Marta Pareja-León; Mónica Riaza-Gómez; María Concepción Ortiz-Barquero; Juan Antonio León-Luis; María Jesús Fernández-Aceñero; María Ángeles Muñoz-Fernández; Pilar Catalán-Alonso; Patricia Muñoz-García; Manuel Sánchez-Luna; María Luisa Navarro-Gómez Journal: Pediatr Infect Dis J Date: 2022-05-06 Impact factor: 3.806