Lilly Bogičević1, Leona Pascoe2,3, Thi-Nhu-Ngoc Nguyen2,3, Alice C Burnett3,4,5,6, Marjolein Verhoeven1, Deanne K Thompson3,6,7,8, Jeanie L Y Cheong3,5,9, Terrie E Inder10, Anneloes L van Baar1, Lex W Doyle3,5,6,9, Peter J Anderson2,3. 1. Child and Adolescent Studies, Utrecht University, Utrecht, The Netherlands. 2. Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Melbourne, Victoria, Australia. 3. Victorian Infant Brain Studies (VIBeS), Murdoch Children's Research Institute, Melbourne, Victoria, Australia. 4. Royal Children's Hospital, Melbourne, Victoria, Australia. 5. Neonatal Services, Royal Women's Hospital, Melbourne, Victoria, Australia. 6. Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia. 7. Developmental Imaging, Murdoch Children's Research Institute, Melbourne, Victoria, Australia. 8. Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia. 9. Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Victoria, Australia. 10. Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Abstract
OBJECTIVE: To identify attention profiles at 7 and 13 years, and transitions in attention profiles over time in children born very preterm (VP; <30 weeks' gestation) and full term (FT), and examine predictors of attention profiles and transitions. METHODS: Participants were 167 VP and 60 FT children, evaluated on profiles across five attention domains (selective, shifting and divided attention, processing speed, and behavioral attention) at 7 and 13 years using latent profile analyses. Transitions in profiles were assessed with contingency tables. For VP children, biological and social risk factors were tested as predictors with a multinomial logistic regression. RESULTS: At 7 and 13 years, three distinct profiles of attentional functioning were identified. VP children were 2-3 times more likely to show poorer attention profiles compared with FT children. Transition patterns between 7 and 13 years were stable average, stable low, improving, and declining attention. VP children were two times less likely to have a stable average attention pattern and three times more likely to have stable low or improving attention patterns compared with FT children. Groups did not differ in declining attention patterns. For VP children, brain abnormalities on neonatal MRI and greater social risk at 7 years predicted stable low or changing attention patterns over time. CONCLUSIONS: VP children show greater variability in attention profiles and transition patterns than FT children, with almost half of the VP children showing adverse attention patterns over time. Early brain pathology and social environment are markers for attentional functioning.
OBJECTIVE: To identify attention profiles at 7 and 13 years, and transitions in attention profiles over time in children born very preterm (VP; <30 weeks' gestation) and full term (FT), and examine predictors of attention profiles and transitions. METHODS: Participants were 167 VP and 60 FT children, evaluated on profiles across five attention domains (selective, shifting and divided attention, processing speed, and behavioral attention) at 7 and 13 years using latent profile analyses. Transitions in profiles were assessed with contingency tables. For VP children, biological and social risk factors were tested as predictors with a multinomial logistic regression. RESULTS: At 7 and 13 years, three distinct profiles of attentional functioning were identified. VP children were 2-3 times more likely to show poorer attention profiles compared with FT children. Transition patterns between 7 and 13 years were stable average, stable low, improving, and declining attention. VP children were two times less likely to have a stable average attention pattern and three times more likely to have stable low or improving attention patterns compared with FT children. Groups did not differ in declining attention patterns. For VP children, brain abnormalities on neonatal MRI and greater social risk at 7 years predicted stable low or changing attention patterns over time. CONCLUSIONS: VP children show greater variability in attention profiles and transition patterns than FT children, with almost half of the VP children showing adverse attention patterns over time. Early brain pathology and social environment are markers for attentional functioning.
Authors: Ralica Dimitrova; Maximilian Pietsch; Judit Ciarrusta; Sean P Fitzgibbon; Logan Z J Williams; Daan Christiaens; Lucilio Cordero-Grande; Dafnis Batalle; Antonios Makropoulos; Andreas Schuh; Anthony N Price; Jana Hutter; Rui Pag Teixeira; Emer Hughes; Andrew Chew; Shona Falconer; Olivia Carney; Alexia Egloff; J-Donald Tournier; Grainne McAlonan; Mary A Rutherford; Serena J Counsell; Emma C Robinson; Joseph V Hajnal; Daniel Rueckert; A David Edwards; Jonathan O'Muircheartaigh Journal: Neuroimage Date: 2021-08-20 Impact factor: 6.556
Authors: Marion Bailhache; Maeva Monnier; Flore Moulin; Xavier Thierry; Stéphanie Vandentorren; Sylvana M Côté; Bruno Falissard; Thierry Simeon; Bertrand Geay; Laetitia Marchand; Marie N Dufourg; Marie A Charles; Pierre Y Ancel; Maria Melchior; Alexandra Rouquette; Cédric Galera Journal: Pediatr Res Date: 2022-03-30 Impact factor: 3.756