| Literature DB >> 33477891 |
Silmar Baptista Nunes1, Katharine Valéria Saraiva Hodel2, Giulia da Costa Sacramento2, Pollyana da Silva Melo3, Fernando Luiz Pellegrini Pessoa1, Josiane Dantas Viana Barbosa1,2, Roberto Badaró1,2, Bruna Aparecida Souza Machado1,2.
Abstract
One of the major benefits of biomedicine is the use of biocomposites as wound dressings to help improve the treatment of injuries. Therefore, the main objective of this study was to develop and characterize biocomposites based on bacterial cellulose (BC) with different concentrations of collagen and starch and characterize their thermal, morphological, mechanical, physical, and barrier properties. In total, nine samples were produced with fixed amounts of glycerol and BC and variations in the amount of collagen and starch. The water activity (0.400-0.480), water solubility (12.94-69.7%), moisture (10.75-20.60%), thickness (0.04-0.11 mm), water vapor permeability (5.59-14.06 × 10-8 g·mm/m2·h·Pa), grammage (8.91-39.58 g·cm-2), opacity (8.37-36.67 Abs 600 nm·mm-1), elongation (4.81-169.54%), and tensile strength (0.99-16.32 MPa) were evaluated and defined. In addition, scanning electron microscopy showed that adding biopolymers in the cellulose matrix made the surface compact, which also influenced the visual appearance. Thus, the performance of the biocomposites was directly influenced by their composition. The performance of the different samples obtained resulted in them having different potentials for application considering the injury type. This provides a solution for the ineffectiveness of traditional dressings, which is one of the great problems of the biomedical sector.Entities:
Keywords: bacterial cellulose; biopolymers; collagen; starch; wound dressing
Year: 2021 PMID: 33477891 PMCID: PMC7833372 DOI: 10.3390/ma14020458
Source DB: PubMed Journal: Materials (Basel) ISSN: 1996-1944 Impact factor: 3.623