Literature DB >> 33477785

Trending Topics on Coumarin and Its Derivatives in 2020.

Aitor Carneiro1, Maria João Matos1,2, Eugenio Uriarte1,3, Lourdes Santana1.   

Abstract

Coumarins are naturally occurring molecules with a versatile range of activities. Their structural and physicochemical characteristics make them a privileged scaffold in medicinal chemistry and chemical biology. Many research articles and reviews compile information on this important family of compounds. In this overview, the most recent research papers and reviews from 2020 are organized and analyzed, and a discussion on these data is included. Multiple electronic databases were scanned, including SciFinder, Mendeley, and PubMed, the latter being the main source of information. Particular attention was paid to the potential of coumarins as an important scaffold in drug design, as well as fluorescent probes for decaging of prodrugs, metal detection, and diagnostic purposes. Herein we do an analysis of the trending topics related to coumarin and its derivatives in the broad field of drug discovery.

Entities:  

Keywords:  biological applications; coumarins; drug discovery; fluorescent probes

Year:  2021        PMID： 33477785      PMCID： PMC7832358          DOI： 10.3390/molecules26020501

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  73 in total

1.  ROS Inhibitory Activity and Cytotoxicity Evaluation of Benzoyl, Acetyl, Alkyl Ester, and Sulfonate Ester Substituted Coumarin Derivatives.

Authors:  Uzma Salar; Khalid M Khan; Almas Jabeen; Aisha Faheem; Farwa Naqvi; Shakil Ahmed; Erum Iqbal; Farman Ali; Shahnaz Perveen
Journal:  Med Chem       Date:  2020       Impact factor: 2.745

2.  A FRET-based ratiometric fluorescent probe to detect cysteine metabolism in mitochondria.

Authors:  Xiaojing Han; Zhiyao Zhai; Xiaopeng Yang; Di Zhang; Jun Tang; Jianming Zhu; Xiaofei Zhu; Yong Ye
Journal:  Org Biomol Chem       Date:  2020-02-19       Impact factor: 3.876

3.  New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation.

Authors:  Baijayantimala Swain; Andrea Angeli; Priti Singh; Claudiu T Supuran; Mohammed Arifuddin
Journal:  Bioorg Med Chem       Date:  2020-06-18       Impact factor: 3.641

4.  Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson's disease therapy.

Authors:  Fernanda Rodríguez-Enríquez; María Carmen Costas-Lago; Pedro Besada; Miguel Alonso-Pena; Iria Torres-Terán; Dolores Viña; José Ángel Fontenla; Mattia Sturlese; Stefano Moro; Elias Quezada; Carmen Terán
Journal:  Bioorg Chem       Date:  2020-09-02       Impact factor: 5.275

5.  Fluorescence "Turn On-Off" Sensing of Copper (II) Ions Utilizing Coumarin-Based Chemosensor: Experimental Study, Theoretical Calculation, Mineral and Drinking Water Analysis.

Authors:  Fatma Nur Arslan; Gonul Akin Geyik; Kenan Koran; Furkan Ozen; Duygu Aydin; Şükriye Nihan Karuk Elmas; Ahmet Orhan Gorgulu; Ibrahim Yilmaz
Journal:  J Fluoresc       Date:  2020-02-03       Impact factor: 2.217

6.  Coumarin Thiourea-Based Fluorescent Turn-on Hg2+ Probe That Can Be Utilized in a Broad pH Range 1-11.

Authors:  Zhixiu Pan; Zhenxiang Xu; Jie Chen; Luping Hu; Hongqi Li; Xin Zhang; Xucheng Gao; Mengxuan Wang; Jian Zhang
Journal:  J Fluoresc       Date:  2020-03-07       Impact factor: 2.217

7.  Targeted photoresponsive carbazole-coumarin and drug conjugates for efficient combination therapy in leukemia cancer cells.

Authors:  Bing-Yen Wang; Yen-Cheng Lin; Yi-Ting Lai; Jia-Yu Ou; Wen-Wei Chang; Chih-Chien Chu
Journal:  Bioorg Chem       Date:  2020-05-05       Impact factor: 5.275

8.  New Copper(I) Complex with a Coumarin as Ligand with Antibacterial Activity against Flavobacterium psychrophilum.

Authors:  Maialen Aldabaldetrecu; Mick Parra; Sarita Soto; Pablo Arce; Mario Tello; Juan Guerrero; Brenda Modak
Journal:  Molecules       Date:  2020-07-13       Impact factor: 4.411

Review 9.  Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway.

Authors:  Emad H M Hassanein; Ahmed M Sayed; Omnia E Hussein; Ayman M Mahmoud
Journal:  Oxid Med Cell Longev       Date:  2020-04-22       Impact factor: 6.543
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  14 in total

1.  Design, Spectroscopy, and Assessment of Cholinesterase Inhibition and Antimicrobial Activities of Novel Coumarin-Thiadiazole Hybrids.

Authors:  Dariusz Karcz; Karolina Starzak; Ewa Ciszkowicz; Katarzyna Lecka-Szlachta; Daniel Kamiński; Bernadette Creaven; Anna Miłoś; Hollie Jenkins; Lidia Ślusarczyk; Arkadiusz Matwijczuk
Journal:  Int J Mol Sci       Date:  2022-06-05       Impact factor: 6.208

2.  Design, Synthesis, and Anti-Inflammatory Activity of Some Coumarin Schiff Base Derivatives: In silico and in vitro Study.

Authors:  Shokhan J Hamid; Twana Salih
Journal:  Drug Des Devel Ther       Date:  2022-07-14       Impact factor: 4.319

3.  Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines.

Authors:  Eva Konkoľová; Monika Hudáčová; Slávka Hamuľaková; Rastislav Jendželovský; Jana Vargová; Juraj Ševc; Peter Fedoročko; Mária Kožurková
Journal:  Molecules       Date:  2021-02-20       Impact factor: 4.411

4.  COUPY Coumarins as Novel Mitochondria-Targeted Photodynamic Therapy Anticancer Agents.

Authors:  Enrique Ortega-Forte; Anna Rovira; Albert Gandioso; Joaquín Bonelli; Manel Bosch; José Ruiz; Vicente Marchán
Journal:  J Med Chem       Date:  2021-11-19       Impact factor: 7.446

5.  Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding.

Authors:  Silvija Maračić; Petra Grbčić; Suresh Shammugam; Marijana Radić Stojković; Krešimir Pavelić; Mirela Sedić; Sandra Kraljević Pavelić; Silvana Raić-Malić
Journal:  Molecules       Date:  2021-11-22       Impact factor: 4.411

Review 6.  A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties.

Authors:  Łukasz Balewski; Sylwia Szulta; Aleksandra Jalińska; Anita Kornicka
Journal:  Front Chem       Date:  2021-12-01       Impact factor: 5.221

7.  Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin.

Authors:  Marco Mellado; César González; Jaime Mella; Luis F Aguilar; Ismail Celik; Fernanda Borges; Eugenio Uriarte; Giovanna Delogu; Dolores Viña; Maria J Matos
Journal:  Molecules       Date:  2022-01-29       Impact factor: 4.411

8.  An Efficient and Versatile Deep Eutectic Solvent-Mediated Green Method for the Synthesis of Functionalized Coumarins.

Authors:  Ishfaq Ahmad Rather; Rashid Ali
Journal:  ACS Omega       Date:  2022-03-15

9.  Monoterpene-Containing Substituted Coumarins as Inhibitors of Respiratory Syncytial Virus (RSV) Replication.

Authors:  Tatyana M Khomenko; Anna A Shtro; Anastasia V Galochkina; Yulia V Nikolaeva; Galina D Petukhova; Sophia S Borisevich; Dina V Korchagina; Konstantin P Volcho; Nariman F Salakhutdinov
Journal:  Molecules       Date:  2021-12-10       Impact factor: 4.411

10.  Twice as Nice: The Duff Formylation of Umbelliferone Revised.

Authors:  Vladislav V Skarga; Vadim V Negrebetsky; Yuri I Baukov; Mikhail V Malakhov
Journal:  Molecules       Date:  2021-12-10       Impact factor: 4.411
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