Literature DB >> 33475648

Rational design of a lysosome-targeting and near-infrared absorbing Ru(ii)-BODIPY conjugate for photodynamic therapy.

Liping Qiao1, Jiangping Liu, Yunhong Han, Fangmian Wei, Xinxing Liao, Cheng Zhang, Lina Xie, Liangnian Ji, Hui Chao.   

Abstract

A Ru(ii)-BODIPY conjugate has been rationally designed and exhibits an intense absorption in the NIR region to boost lysosome-targeted PDT in vitro and in vivo. The advantages of Ru(ii) and BODIPY were successfully instilled into the conjugate to yield highly effective PDT efficacy against malignant melanoma A375 cells (PI = 3448) and A375 mice xenografts.

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Year:  2021        PMID： 33475648     DOI： 10.1039/d0cc06926d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis.

Authors:  Alejandro Prieto-Castañeda; Fernando García-Garrido; Carolina Díaz-Norambuena; Blanca Escriche-Navarro; Alba García-Fernández; Jorge Bañuelos; Esther Rebollar; Inmaculada García-Moreno; Ramón Martínez-Máñez; Santiago de la Moya; Antonia R Agarrabeitia; María J Ortiz
Journal:  Org Lett       Date:  2022-05-16       Impact factor: 6.072

2.  How Computations Can Assist the Rational Design of Drugs for Photodynamic Therapy: Photosensitizing Activity Assessment of a Ru(II)-BODIPY Assembly.

Authors:  Fortuna Ponte; Davide Maria Scopelliti; Nico Sanna; Emilia Sicilia; Gloria Mazzone
Journal:  Molecules       Date:  2022-09-01       Impact factor: 4.927

Review 3.  Photodynamic Therapy-Current Limitations and Novel Approaches.

Authors:  Gurcan Gunaydin; M Emre Gedik; Seylan Ayan
Journal:  Front Chem       Date:  2021-06-10       Impact factor: 5.221
  3 in total

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