Literature DB >> 33475635

Genetically encoding ε-N-benzoyllysine in proteins.

Yanli Ji1, Conghui Ren, Hui Miao, Zhili Pang, Ruotong Xiao, Xiaochen Yang, Weimin Xuan.   

Abstract

Lysine ε-N-benzoylation is a recently identified PTM occurring on histone proteins, and herein we genetically encoded ε-N-benzoyl-lysine (BzK) into recombinant proteins in E. coli and mammalian cells, and applied it for the modification of histone proteins and the analysis of sirtuin debenzoylase activity.

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Year:  2021        PMID: 33475635     DOI: 10.1039/d0cc07954e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Global profiling of regulatory elements in the histone benzoylation pathway.

Authors:  Duo Wang; Fuxiang Yan; Ping Wu; Kexue Ge; Muchun Li; Tingting Li; Ying Gao; Chao Peng; Yong Chen
Journal:  Nat Commun       Date:  2022-03-16       Impact factor: 14.919

2.  Genetic Incorporation of ϵ-N-Benzoyllysine by Engineering Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase.

Authors:  Li Cao; Jun Liu; Farid Ghelichkhani; Sharon Rozovsky; Lei Wang
Journal:  Chembiochem       Date:  2021-06-21       Impact factor: 3.461

  2 in total

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