Literature DB >> 33474656

The effective natural compounds for inhibiting Cervical cancer.

Faik Gökalp1.   

Abstract

The secondary compounds found in plants are of great importance in the treatment of many diseases in medicine and pharmacy. Some of these compounds have been reported to exhibit anticarcinogenic effects by inhibiting the growth and metastatic potential of cancer cells. Consumption of the required amount of vegetables and fruits appears to have a protective effect of these secondary compounds on cancer, since most of these drugs are synthesized from natural or natural origin compounds. Secondary compounds in medicinal plants have been found to have an antiproliferative effect by increasing the expression of p53 in cervical cancer cells and decreasing the expression of cyclin D1, one of the cell proliferation markers. The most important step in the fight against cancer is the development of drugs that are selectively targeted against tumor cells and targeting cancer cells to reduce damage to normal cells and prevent the growth and spread of cancer cells. Molecular insertion test is an effective tool for evaluating the bioactivity of possible molecules. In this study, the effect of natural compounds in some medicinal plants in inhibiting cervical cancer, the points where they are effective using docking has been investigated.

Entities:  

Keywords:  Carvacrol; Docking; P53 carcinoma cell; Thymol; Tymoquinone

Year:  2021        PMID: 33474656     DOI: 10.1007/s12032-021-01456-3

Source DB:  PubMed          Journal:  Med Oncol        ISSN: 1357-0560            Impact factor:   3.064


  2 in total

1.  Cucurbitacin I induces protective autophagy in glioblastoma in vitro and in vivo.

Authors:  Guang Yuan; Shao-Feng Yan; Hao Xue; Ping Zhang; Jin-Tang Sun; Gang Li
Journal:  J Biol Chem       Date:  2014-03-05       Impact factor: 5.157

Review 2.  Anticancer activity of thymol: A literature-based review and docking study with Emphasis on its anticancer mechanisms.

Authors:  Muhammad T Islam; Abul B R Khalipha; Rajat Bagchi; Milon Mondal; Shanita Z Smrity; Shaikh J Uddin; Jamil A Shilpi; Razina Rouf
Journal:  IUBMB Life       Date:  2018-10-11       Impact factor: 3.885

  2 in total
  2 in total

Review 1.  Potential Mechanisms of Plant-Derived Natural Products in the Treatment of Cervical Cancer.

Authors:  Meizhu He; Lijie Xia; Jinyao Li
Journal:  Biomolecules       Date:  2021-10-18

2.  Trichosanthin inhibits cervical cancer by regulating oxidative stress-induced apoptosis.

Authors:  Chenglu Zhu; Cuilan Zhang; Xiaoming Cui; Jing Wu; Zhizhu Cui; Xiaojuan Shen
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

  2 in total

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