Woo Yeup Jeong1, Moon Sung Kang2, Haeni Lee2, Jong Hun Lee3, Jeesu Kim2, Dong-Wook Han2, Ki Su Kim1. 1. School of Chemical Engineering, College of Engineering, Pusan National University, Busan 46241, Korea. 2. Department of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan 46241, Korea. 3. Department of Food Science and Biotechnology, Gachon University, Seongnam, Gyeonggi 13120, Korea.
Abstract
A variety of 2D materials have been developed for therapeutic biomedical studies. Because of their excellent physicochemical properties, 2D materials can be used as carriers for delivering therapeutic agents into a lesion, leading to phototherapy. Various optical imaging techniques have been used for the monitoring of the treatment process. Among these, photoacoustic imaging has unique advantages including relatively deep imaging depth and large field of view with high spatial resolution. In this review article, we summarize the types of photoacoustic imaging systems used for phototherapy monitoring, then we explore contrast-enhanced photoacoustic images using 2D materials. Finally, photoacoustic image-guided phototherapies are discussed. We conclude that 2D material-based phototherapy can be efficiently monitored by photoacoustic imaging techniques.
A variety of pan class="Chemical">2D materials have been developed for therapeutic biomedical studies. Because of their excellent physicochemical properties, 2D materials can be used as carriers for delivering therapeutic agents into a lesion, leading to phototherapy. Various optical imaging techniques have been used for the monitoring of the treatment process. Among these, photoacoustic imaging has unique advantages including relatively deep imaging depth and large field of view with high spatial resolution. In this review article, we summarize the types of photoacoustic imaging systems used for phototherapy monitoring, then we explore contrast-enhanced photoacoustic images using 2D materials. Finally, photoacoustic image-guided phototherapies are discussed. We conclude that 2D material-based phototherapy can be efficiently monitored by photoacoustic imaging techniques.
Authors: Hans F Wehrl; Stefan Wiehr; Mathew R Divine; Sergios Gatidis; Grant T Gullberg; Florian C Maier; Anna-Maria Rolle; Johannes Schwenck; Wolfgang M Thaiss; Bernd J Pichler Journal: J Nucl Med Date: 2014-05-15 Impact factor: 10.057