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Literature DB >> 33467532

Lipid Metabolism as a Targetable Metabolic Vulnerability in Colorectal Cancer.

Abstract

Colorectal cancer (CRC), the second leading cause of cancer-related deaths according to the World Health Organization, remains a substantial public health problem worldwide [...].

Entities: Chemical Disease Gene Species

Year: 2021 PMID： 33467532 PMCID： PMC7830794 DOI： 10.3390/cancers13020301

Source DB: PubMed Journal: Cancers (Basel) ISSN： 2072-6694 Impact factor: 6.639

55 in total

Review 1. Colorectal Cancer in Young Adults.

Authors: Anand Venugopal; Elena M Stoffel
Journal: Curr Treat Options Gastroenterol Date: 2019-03

2. LC-MS-based lipid profile in colorectal cancer patients: TAGs are the main disturbed lipid markers of colorectal cancer progression.

Authors: Tong Liu; Feng Peng; Jing Yu; Zhirong Tan; Tai Rao; Yao Chen; Yicheng Wang; Zhaoqian Liu; Honghao Zhou; Jingbo Peng
Journal: Anal Bioanal Chem Date: 2019-06-14 Impact factor: 4.142

Review 3. Increased lipogenesis in cancer cells: new players, novel targets.

Authors: Johannes V Swinnen; Koen Brusselmans; Guido Verhoeven
Journal: Curr Opin Clin Nutr Metab Care Date: 2006-07 Impact factor: 4.294

4. Biochemistry, molecular biology, and pharmacology of fatty acid synthase, an emerging therapeutic target and diagnosis/prognosis marker.

Authors: Hailan Liu; Jing-Yuan Liu; Xi Wu; Jian-Ting Zhang
Journal: Int J Biochem Mol Biol Date: 2010-07-18

Review 5. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis.

Authors: Javier A Menendez; Ruth Lupu
Journal: Nat Rev Cancer Date: 2007-10 Impact factor: 60.716

6. Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer.

Authors: Yekaterina Y Zaytseva; Victoria A Elliott; Piotr Rychahou; W Conan Mustain; Ji Tae Kim; Joseph Valentino; Tianyan Gao; Kathleen L O'Connor; Janna M Neltner; Eun Y Lee; Heidi L Weiss; B Mark Evers
Journal: Carcinogenesis Date: 2014-02-07 Impact factor: 4.944

7. Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression.

Authors: Richard Ventura; Kasia Mordec; Joanna Waszczuk; Zhaoti Wang; Julie Lai; Marina Fridlib; Douglas Buckley; George Kemble; Timothy S Heuer
Journal: EBioMedicine Date: 2015-07-02 Impact factor: 8.143

8. Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer.

Authors: Yekaterina Y Zaytseva; Piotr G Rychahou; Anh-Thu Le; Timothy L Scott; Robert M Flight; Ji Tae Kim; Jennifer Harris; Jinpeng Liu; Chi Wang; Andrew J Morris; Theru A Sivakumaran; Teresa Fan; Hunter Moseley; Tianyan Gao; Eun Y Lee; Heidi L Weiss; Timothy S Heuer; George Kemble; Mark Evers
Journal: Oncotarget Date: 2018-05-15

9. ACLY facilitates colon cancer cell metastasis by CTNNB1.

Authors: Jun Wen; Xuejie Min; Mengqin Shen; Qian Hua; Yuan Han; Li Zhao; Liu Liu; Gang Huang; Jianjun Liu; Xiaoping Zhao
Journal: J Exp Clin Cancer Res Date: 2019-09-12

10. Association of Dietary Inflammatory Potential With Colorectal Cancer Risk in Men and Women.

Authors: Fred K Tabung; Li Liu; Weike Wang; Teresa T Fung; Kana Wu; Stephanie A Smith-Warner; Yin Cao; Frank B Hu; Shuji Ogino; Charles S Fuchs; Edward L Giovannucci
Journal: JAMA Oncol Date: 2018-03-01 Impact factor: 31.777

9 in total

Review 1. Colorectal Cancer in Younger Adults.

Authors: Pooja Dharwadkar; Timothy A Zaki; Caitlin C Murphy
Journal: Hematol Oncol Clin North Am Date: 2022-05-13 Impact factor: 2.861

2. Tissue-Specific Downregulation of Fatty Acid Synthase Suppresses Intestinal Adenoma Formation via Coordinated Reprograming of Transcriptome and Metabolism in the Mouse Model of Apc-Driven Colorectal Cancer.

Authors: James Drury; Lyndsay E A Young; Timothy L Scott; Courtney O Kelson; Daheng He; Jinpeng Liu; Yuanyan Wu; Chi Wang; Heidi L Weiss; Teresa Fan; Matthew S Gentry; Ramon Sun; Yekaterina Y Zaytseva
Journal: Int J Mol Sci Date: 2022-06-10 Impact factor: 6.208

Review 3. A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis.

Authors: Tomasz Sawicki; Monika Ruszkowska; Anna Danielewicz; Ewa Niedźwiedzka; Tomasz Arłukowicz; Katarzyna E Przybyłowicz
Journal: Cancers (Basel) Date: 2021-04-22 Impact factor: 6.639

4. Rewired lipid metabolism as an actionable vulnerability of aggressive colorectal carcinoma.

Authors: Daria Capece; Guido Franzoso
Journal: Mol Cell Oncol Date: 2022-01-27

5. EPHX2 Inhibits Colon Cancer Progression by Promoting Fatty Acid Degradation.

Authors: Yiran Zhou; Xiao Li; Aoran Guan; Haodong Zhou; Yankun Zhu; Ruotian Wang; Ruhong Li
Journal: Front Oncol Date: 2022-03-30 Impact factor: 6.244

6. Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells.

Authors: Martina Karasová; Jiřina Procházková; Zuzana Tylichová; Radek Fedr; Miroslav Ciganek; Miroslav Machala; Zdeněk Dvořák; Barbora Vyhlídalová; Iveta Zůvalová; Jiří Ehrmann; Jan Bouchal; Zdeněk Andrysík; Jan Vondráček
Journal: Cancers (Basel) Date: 2022-08-31 Impact factor: 6.575