Literature DB >> 33467069

Feasibility and Safety of Transjugular Liver Biopsy for Japanese Patients with Chronic Liver Diseases.

Makoto Iijima1, Takahiro Arisaka1, Akira Yamamiya1, Keiichi Tominaga1, Kazunori Nagashima1, Akira Kanamori1, Satoshi Masuyama1, Yuichi Majima1, Kenichi Goda1, Kazuyuki Ishida2, Atsushi Irisawa1.   

Abstract

BACKGROUND AND STUDY AIM: Transjugular liver biopsy (TJLB) can be used in patients who are ineligible for percutaneous liver biopsy (PLB) with acute and chronic hepatic disease. This study aimed to evaluate the usefulness and safety of TJLB in patients who were not indicated for PLB.
METHODS: Between July 2014 and February 2019, a total of 134 patients underwent liver biopsies at our institution. Among these, PLB was performed in 110 patients and TJLB in 24 patients. A retrospective comparison of clinical results in these patients was then performed. The primary endpoints of this study were the utility and safety of TJLB in patients who were not indicated for PLB.
RESULTS: The procedural success rate was 100% in both groups. The clinical response rate and the effective tissue sampling rate were 100% in the TJLB group and 97% in the PLB group (p = 0.55). There was no difference in the number of portal fields examined retrospectively between the two groups. No serious adverse events were observed in either group.
CONCLUSIONS: It is suggested that TJLB is useful because it can be safely performed in patients with poor general condition who are not indicated for PLB.

Entities:  

Keywords:  acute hepatic disease; chronic hepatic disease; percutaneous liver biopsy; transjugular liver biopsy

Year:  2021        PMID: 33467069      PMCID: PMC7829793          DOI: 10.3390/diagnostics11010131

Source DB:  PubMed          Journal:  Diagnostics (Basel)        ISSN: 2075-4418


  32 in total

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