Literature DB >> 33467041

Observations on the Occurrence, Transmission and Management of the COVID-19 Pandemic Derived from Physics.

John G Ingersoll1.   

Abstract

Three important observations derived from the ongoing COVID-19 pandemic could result in the development of novel approaches to deal with it and avoid or at least minimize the occurrence and impact of future outbreaks. First, the dramatic increase in pandemics in the past decade alone suggests that the current relationship of humans with the environment is quickly becoming unstable, with potentially catastrophic consequences. In order to reduce the toll in life and property, we would need to shift our emphasis from control of nature to a symbiosis with nature. This, then, can become the new framework for dealing effectively with environmental issues such as climate change, whereby properly applied medical science would provide the necessary impetus for action. Second, the existence of superspreaders of infection among populations in this pandemic requires that we develop objective tests, most likely of a genetic nature, to identify them rather than apply indiscriminate and draconian controls across the board. Not identifying superspreaders in a timely fashion could allow this pandemic to turn into a black swan event, with a catastrophic impact on society. Third, we need to refocus our efforts in dealing with this pandemic from the virus itself to the human hosts. An objective morbidity risk index can be developed such that most of us can go about our daily business without the fear of becoming seriously ill, while measures can be implemented to protect those who are most vulnerable to this virus. These observations point clearly to a need for a paradigm shift.

Entities:  

Keywords:  ACE-2 marker; COVID-19; SARS-CoV-2; infection pathway; morbidity risk index; nature; power law; quantum world; superspreader; symbiosis

Year:  2021        PMID: 33467041      PMCID: PMC7838878          DOI: 10.3390/diseases9010009

Source DB:  PubMed          Journal:  Diseases        ISSN: 2079-9721


  10 in total

1.  ["Politics is nothing else than large scale medicine"--Rudolf Virchow and his role in the development of social medicine].

Authors:  R Wittern-Sterzel
Journal:  Verh Dtsch Ges Pathol       Date:  2003

2.  Politics is nothing but medicine at a larger scale: reflections on public health's biggest idea.

Authors:  J P Mackenbach
Journal:  J Epidemiol Community Health       Date:  2008-12-03       Impact factor: 3.710

3.  Some quantum weirdness in physiology.

Authors:  Peter G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-08       Impact factor: 11.205

Review 4.  "Herd immunity": a rough guide.

Authors:  Paul Fine; Ken Eames; David L Heymann
Journal:  Clin Infect Dis       Date:  2011-04-01       Impact factor: 9.079

5.  The placebo effect.

Authors:  W A Brown
Journal:  Sci Am       Date:  1998-01       Impact factor: 2.142

6.  History is repeating itself: Probable zoonotic spillover as the cause of the 2019 novel Coronavirus Epidemic

Authors:  Alfonso J Rodriguez-Morales; D Katterine Bonilla-Aldana; Graciela Josefina Balbin-Ramon; Ali A Rabaan; Ranjit Sah; Alberto Paniz-Mondolfi; Pasquale Pagliano; Silvano Esposito
Journal:  Infez Med       Date:  2020-03-01

7.  SARS-CoV-2 Infectivity and Neurological Targets in the Brain.

Authors:  Walter J Lukiw; Aileen Pogue; James M Hill
Journal:  Cell Mol Neurobiol       Date:  2020-08-25       Impact factor: 5.046

Review 8.  Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: a systematic review of the literature.

Authors:  Matthew Biggerstaff; Simon Cauchemez; Carrie Reed; Manoj Gambhir; Lyn Finelli
Journal:  BMC Infect Dis       Date:  2014-09-04       Impact factor: 3.090

Review 9.  Emerging Pandemic Diseases: How We Got to COVID-19.

Authors:  David M Morens; Anthony S Fauci
Journal:  Cell       Date:  2020-08-15       Impact factor: 41.582

  10 in total

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