Literature DB >> 33466154

Ectopic thyroid gland located on the L4 vertebral body: A case report.

Qihuan Lin1, Qilu Gao, Rong Fan, Li Zhang, Weijia Li, Hongkun Liu, Wenbin Zheng.   

Abstract

RATIONALE: The prevalence of ectopic thyroid is extremely low, with the condition observed in approximately 1 in 100,000 to 300,000 people. Thyroid gland ectopia develops as a result of the presence of developmental abnormalities during the migration of the thyroid anlage from the floor of the primitive foregut to its final position in the neck. Ectopic thyroid tissue is commonly observed in the lingual region, but can also present in other head and neck regions, as well as regions located at a large distance from the neck. PATIENT CONCERNS: A 67-year-old woman who had experienced left lumbago and leg pain was transferred to our hospital following the worsening of her lumbago-related symptoms in the 2 months preceding her presentation. Seven years ago, the patient had recurrent lumbago and leg pain without obvious inducement, and visited a local clinic for treatment. The severity of her symptoms fluctuated; their intensity increased after participation in activities and decreased after rest. DIAGNOSES: The patient was diagnosed as having an ectopic thyroid gland that was located on the L4 vertebral body.
INTERVENTIONS: The patient chose to undergo surgery, with supportive care, following tumor discovery. OUTCOMES: After surgical treatment, the degree of lumbar spinal stenosis improved, and the patient's clinical symptoms were alleviated. LESSONS: Clinically, ectopic goiter is diagnosed through radionuclide thyroid imaging, ultrasound examination, computed tomography, magnetic resonance imaging, and biopsy pathology. However, the imaging manifestations in this case were atypical, leading to greater diagnostic difficulties. A conclusion was finally reached based on pathology.
Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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Mesh:

Year:  2021        PMID: 33466154      PMCID: PMC7808474          DOI: 10.1097/MD.0000000000024042

Source DB:  PubMed          Journal:  Medicine (Baltimore)        ISSN: 0025-7974            Impact factor:   1.817


  7 in total

Review 1.  Ectopic thyroid: etiology, pathology and management.

Authors:  Nasiru Akamnu Ibrahim; Idowu Olusegun Fadeyibi
Journal:  Hormones (Athens)       Date:  2011 Oct-Dec       Impact factor: 2.885

2.  Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity.

Authors:  Helmut Grasberger; Usanee Ringkananont; Paule Lefrancois; Marc Abramowicz; Gilbert Vassart; Samuel Refetoff
Journal:  Mol Endocrinol       Date:  2005-02-17

3.  Agenesis of Isthmus of Thyroid Gland in the Presence of Ectopic Thyroid Tissue Associated with Papillary Carcinoma.

Authors:  Kesici Ugur; Kesici Sevgi; Kesicioglu Tugrul; Demet Sengul
Journal:  J Coll Physicians Surg Pak       Date:  2019-01       Impact factor: 0.711

Review 4.  Morphological, diagnostic and surgical features of ectopic thyroid gland: a review of literature.

Authors:  Germano Guerra; Mariapia Cinelli; Massimo Mesolella; Domenico Tafuri; Aldo Rocca; Bruno Amato; Sandro Rengo; Domenico Testa
Journal:  Int J Surg       Date:  2014-06-02       Impact factor: 6.071

5.  A mouse model demonstrates a multigenic origin of congenital hypothyroidism.

Authors:  Elena Amendola; Pasquale De Luca; Paolo Emidio Macchia; Daniela Terracciano; Annamaria Rosica; Gennaro Chiappetta; Shioko Kimura; Ahmed Mansouri; Andrea Affuso; Claudio Arra; Vincenzo Macchia; Roberto Di Lauro; Mario De Felice
Journal:  Endocrinology       Date:  2005-09-08       Impact factor: 4.736

6.  The value of scintigraphy, computed tomography, magnetic resonance imaging, and single-photon emission computed tomography/computed tomography for the diagnosis of ectopic thyroid in the head and neck: A STROBE-compliant retrospective study.

Authors:  Feng Xu; Ziyang Shao; Gongxing Yang; Aichun Gu; Mengda Jiang; Yifan Pan; Yubo Ma
Journal:  Medicine (Baltimore)       Date:  2018-03       Impact factor: 1.889

7.  New insight into ectopic thyroid glands between the neck and maxillofacial region from a 42-case study.

Authors:  Ting Gu; Boren Jiang; Ningjian Wang; Fangzhen Xia; Lizhen Wang; Aichun Gu; Feng Xu; Yongshun Han; Qin Li; Yingli Lu
Journal:  BMC Endocr Disord       Date:  2015-11-18       Impact factor: 2.763

  7 in total

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