Literature DB >> 33464616

Phytochemistry and cardiovascular protective effects of Huang-Qi (Astragali Radix).

Hui-Fei Su1, Sharpkate Shaker1, Yi Kuang1, Meng Zhang1, Min Ye1,2, Xue Qiao1.   

Abstract

Huang-Qi (Astragali Radix) is an herbal tonic widely used in China and many other countries. It is derived from the roots of Astragalus membranaceus and A. membranaceus var. mongholicus and shows potent cardiovascular protective effects. In this article, we comprehensively reviewed 189 small molecules isolated from the two Astragalus species and discussed the interspecies chemical differences. Moreover, we summarized the pharmacological activities and mechanisms of action of Huang-Qi and its major bioactive compounds for the treatment of cardiovascular diseases. This review covers 171 references published between February 1983 and March 2020.
© 2021 Wiley Periodicals LLC.

Entities:  

Keywords:  zzm321990Astragalus spp.; Astragali Radix; Huang-Qi; cardiovascular diseases; chemical constituents; herbal medicine

Year:  2021        PMID： 33464616     DOI： 10.1002/med.21785

Source DB:  PubMed          Journal:  Med Res Rev        ISSN： 0198-6325            Impact factor:   12.944


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