| Literature DB >> 33462673 |
Rory J Tinker1,2, Antonio Charlys da Costa3, Roozbeh Tahmasebi1, Eric Delwart4,5, Ester Cerdeira Sabino1, Elcio Leal6, Adriana Luchs7, Flavio Augusto de Pádua Milagres8,9, Vanessa Dos Santos Morais1, Ramendra Pati Pandey10, Alexis José-Abrego11, Rafael Brustulin8,9, Maria da Aparecida Rodrigues Teles9, Mariana Sequetin Cunha12, Emerson Luiz Lima Araújo13, Mariela Martínez Gómez14, Xutao Deng4,5.
Abstract
From 2010-2016, a total of 251 stool samples were screened for norovirus using next-generation sequencing (NGS) followed by phylogenetic analysis to investigate the genotypic diversity of noroviruses in rural and low-income urban areas in northern Brazil. Norovirus infection was detected in 19.9% (50/251) of the samples. Eight different genotypes were identified: GII.4_Sydney[P31] (64%, 32/50), GII.6[P7] (14%, 7/50), GII.17[P17] (6%, 3/50), GII.1[P33] (6%, 3/50), GII.3[P16] (4%, 2/50), GII.2[P16] (2%, 1/50), GII.2[P2] (2%, 1/50), and GII.4_New Orleans[P4] (2%, 1/50). Distinct GII.6[P7] variants were recognized, indicating the presence of different co-circulating strains. Elucidating norovirus genetic diversity will improve our understanding of their potential health burden, in particular for the GII.4_Sydney[P31] variant.Entities:
Year: 2021 PMID： 33462673 DOI： 10.1007/s00705-020-04944-5
Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574