Literature DB >> 33460674

Optimal control of the SIR model in the presence of transmission and treatment uncertainty.

Nicole M Gatto1, Henry Schellhorn2.   

Abstract

The COVID-19 pandemic illustrates the importance of treatment-related decision making in populations. This article considers the case where the transmission rate of the disease as well as the eciency of treatments is subject to uncertainty. We consider two dierent regimes, or submodels, of the stochastic SIR model, where the population consists of three groups: susceptible, infected and recovered and dead. In the first regime the proportion of infected is very low, and the proportion of susceptible is very close to 100 with few deaths and where recovered individuals do not acquire immunity. In a second regime, the proportion of infected is moderate, but not negligible. We show that the first regime corresponds almost exactly to a well-known problem in finance, the problem of portfolio and consumption decisions under mean-reverting returns (Wachter, JFQA 2002), for which the optimal control has an analytical solution. We develop a perturbative solution for the second problem. To our knowledge, this paper represents one of the first attempts to develop analytical/perturbative solutions, as opposed to numerical solutions to stochastic SIR models.
Copyright © 2021. Published by Elsevier Inc.

Entities:  

Keywords:  COVID-19; Epidemics; SARS-coV-2; SIR model; Stochastic optimal control

Year:  2021        PMID: 33460674     DOI: 10.1016/j.mbs.2021.108539

Source DB:  PubMed          Journal:  Math Biosci        ISSN: 0025-5564            Impact factor:   2.144


  6 in total

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Authors:  Benny Yong; Jonathan Hoseana; Livia Owen
Journal:  Infect Dis Model       Date:  2022-06-30

2.  Estimating a continuously varying offset between multivariate time series with application to COVID-19 in the United States.

Authors:  Nick James; Max Menzies
Journal:  Eur Phys J Spec Top       Date:  2022-01-11       Impact factor: 2.891

3.  Comparing the dynamics of COVID-19 infection and mortality in the United States, India, and Brazil.

Authors:  Nick James; Max Menzies; Howard Bondell
Journal:  Physica D       Date:  2022-01-19       Impact factor: 2.300

4.  Optimal control of the SIR model with constrained policy, with an application to COVID-19.

Authors:  Yujia Ding; Henry Schellhorn
Journal:  Math Biosci       Date:  2021-12-16       Impact factor: 2.144

5.  Trends in COVID-19 prevalence and mortality: A year in review.

Authors:  Nick James; Max Menzies
Journal:  Physica D       Date:  2021-06-07       Impact factor: 2.300

6.  The second and third waves in India: when will the pandemic be culminated?

Authors:  C Kavitha; A Gowrisankar; Santo Banerjee
Journal:  Eur Phys J Plus       Date:  2021-05-28       Impact factor: 3.911

  6 in total

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