Literature DB >> 33460025

Measurement of Lung Vessel and Epithelial Permeability In Vivo with Evans Blue.

Prestina Smith1, Lauren A Jeffers1, Michael Koval2,3.   

Abstract

Lung fluid balance is maintained in part by the barriers formed by the pulmonary microvasculature and alveolar epithelium. Failure of either of these barriers leads to pulmonary edema, which limits lung function and exacerbates the severity of acute lung injury. Here we describe a method using Evans Blue dye to simultaneously measure the function of vascular and epithelial barriers of murine lungs in vivo.

Entities:  

Keywords:  Acute respiratory distress syndrome; Alveolar epithelium; Lung barrier function; Pulmonary edema; Tight junctions; Vascular endothelium

Mesh:

Substances:

Year:  2021        PMID: 33460025      PMCID: PMC8249315          DOI: 10.1007/7651_2020_345

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  13 in total

Review 1.  Integrated control of lung fluid balance.

Authors:  Dolly Mehta; Jahar Bhattacharya; Michael A Matthay; Asrar B Malik
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2004-12       Impact factor: 5.464

2.  Anti-inflammatory effects of β2 adrenergic receptor agonists in experimental acute lung injury.

Authors:  Markus Bosmann; Jamison J Grailer; Ketong Zhu; Michael A Matthay; J Vidya Sarma; Firas S Zetoune; Peter A Ward
Journal:  FASEB J       Date:  2012-02-07       Impact factor: 5.191

Review 3.  The contribution of epithelial sodium channels to alveolar function in health and disease.

Authors:  Douglas C Eaton; My N Helms; Michael Koval; Hui Fang Bao; Lucky Jain
Journal:  Annu Rev Physiol       Date:  2009       Impact factor: 19.318

Review 4.  Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability.

Authors:  Yulia A Komarova; Kevin Kruse; Dolly Mehta; Asrar B Malik
Journal:  Circ Res       Date:  2017-01-06       Impact factor: 17.367

5.  Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade.

Authors:  Jonathan L Koff; Matt X G Shao; Suil Kim; Iris F Ueki; Jay A Nadel
Journal:  J Immunol       Date:  2006-12-15       Impact factor: 5.422

Review 6.  The acute respiratory distress syndrome: pathogenesis and treatment.

Authors:  Michael A Matthay; Rachel L Zemans
Journal:  Annu Rev Pathol       Date:  2011       Impact factor: 23.472

7.  Effects of different routes of endotoxin injury on barrier function in alcoholic lung syndrome.

Authors:  Prestina Smith; Lauren A Jeffers; Michael Koval
Journal:  Alcohol       Date:  2018-08-22       Impact factor: 2.405

Review 8.  Claudins: Gatekeepers of lung epithelial function.

Authors:  Barbara Schlingmann; Samuel A Molina; Michael Koval
Journal:  Semin Cell Dev Biol       Date:  2015-05-04       Impact factor: 7.727

9.  Calibrated flux measurements reveal a nanostructure-stimulated transcytotic pathway.

Authors:  Tarianna Stewart; William T Koval; Samuel A Molina; Suzanne M Bock; James W Lillard; Russell F Ross; Tejal A Desai; Michael Koval
Journal:  Exp Cell Res       Date:  2017-04-05       Impact factor: 3.905

Review 10.  Albumin as a versatile platform for drug half-life extension.

Authors:  Darrell Sleep; Jason Cameron; Leslie R Evans
Journal:  Biochim Biophys Acta       Date:  2013-04-29
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  1 in total

1.  In vivo evaluation of a lipopolysaccharide-induced ear vascular leakage model in mice using photoacoustic microscopy.

Authors:  Zhe Li; Pengbo He; Yuqing Xu; Yuxiao Deng; Yuan Gao; Sung-Liang Chen
Journal:  Biomed Opt Express       Date:  2022-08-16       Impact factor: 3.562

  1 in total

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