Literature DB >> 33457449

Getting quantitative on the effects of somatic mutation on cancer.

Jeffrey P Townsend1.   

Abstract

Entities:  

Keywords:  cancer genetics; effect size; frequency; natural selection; prevalence; somatic variant; therapeutic development

Year:  2020        PMID： 33457449      PMCID： PMC7781488          DOI： 10.18632/oncoscience.521

Source DB:  PubMed          Journal:  Oncoscience        ISSN： 2331-4737


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  10 in total

1.  Cost of innovation in the pharmaceutical industry.

Authors:  J A DiMasi; R W Hansen; H G Grabowski; L Lasagna
Journal:  J Health Econ       Date:  1991-07       Impact factor: 3.883

2.  Early and multiple origins of metastatic lineages within primary tumors.

Authors:  Zi-Ming Zhao; Bixiao Zhao; Yalai Bai; Atila Iamarino; Stephen G Gaffney; Joseph Schlessinger; Richard P Lifton; David L Rimm; Jeffrey P Townsend
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-08       Impact factor: 11.205

3.  Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C.

Authors:  Vincent L Cannataro; Stephen G Gaffney; Carly Stender; Zi-Ming Zhao; Mark Philips; Andrew E Greenstein; Jeffrey P Townsend
Journal:  Oncogene       Date:  2018-02-16       Impact factor: 9.867

4.  Cancer evolution is associated with pervasive positive selection on globally expressed genes.

Authors:  Sheli L Ostrow; Ruth Barshir; James DeGregori; Esti Yeger-Lotem; Ruth Hershberg
Journal:  PLoS Genet       Date:  2014-03-06       Impact factor: 5.917

5.  Mutational Signatures Are Critical for Proper Estimation of Purifying Selection Pressures in Cancer Somatic Mutation Data When Using the dN/dS Metric.

Authors:  Jimmy Van den Eynden; Erik Larsson
Journal:  Front Genet       Date:  2017-06-08       Impact factor: 4.599

6.  Analysis of mutation, selection, and epistasis: an informed approach to cancer clinical trials.

Authors:  Jon F Wilkins; Vincent L Cannataro; Brian Shuch; Jeffrey P Townsend
Journal:  Oncotarget       Date:  2018-04-27

7.  Wagging the long tail of drivers of prostate cancer.

Authors:  Vincent L Cannataro; Jeffrey P Townsend
Journal:  PLoS Genet       Date:  2019-01-17       Impact factor: 5.917

8.  Universal Patterns of Selection in Cancer and Somatic Tissues.

Authors:  Iñigo Martincorena; Keiran M Raine; Moritz Gerstung; Kevin J Dawson; Kerstin Haase; Peter Van Loo; Helen Davies; Michael R Stratton; Peter J Campbell
Journal:  Cell       Date:  2017-10-19       Impact factor: 41.582

9.  The long tail of oncogenic drivers in prostate cancer.

Authors:  Joshua Armenia; Stephanie A M Wankowicz; David Liu; Jianjiong Gao; Ritika Kundra; Ed Reznik; Walid K Chatila; Debyani Chakravarty; G Celine Han; Ilsa Coleman; Bruce Montgomery; Colin Pritchard; Colm Morrissey; Christopher E Barbieri; Himisha Beltran; Andrea Sboner; Zafeiris Zafeiriou; Susana Miranda; Craig M Bielski; Alexander V Penson; Charlotte Tolonen; Franklin W Huang; Dan Robinson; Yi Mi Wu; Robert Lonigro; Levi A Garraway; Francesca Demichelis; Philip W Kantoff; Mary-Ellen Taplin; Wassim Abida; Barry S Taylor; Howard I Scher; Peter S Nelson; Johann S de Bono; Mark A Rubin; Charles L Sawyers; Arul M Chinnaiyan; Nikolaus Schultz; Eliezer M Van Allen
Journal:  Nat Genet       Date:  2018-04-02       Impact factor: 38.330

10.  Effect Sizes of Somatic Mutations in Cancer.

Authors:  Vincent L Cannataro; Stephen G Gaffney; Jeffrey P Townsend
Journal:  J Natl Cancer Inst       Date:  2018-11-01       Impact factor: 13.506
  10 in total

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